Difference between revisions of "TrpE"
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|style="background:#ABCDEF;" align="center"|'''Function''' || biosynthesis of tryptophan | |style="background:#ABCDEF;" align="center"|'''Function''' || biosynthesis of tryptophan | ||
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+ | |colspan="2" style="background:#FAF8CC;" align="center"| '''Interactions involving this protein in [http://cellpublisher.gobics.de/subtinteract/startpage/start/ ''Subt''Interact]''': [http://cellpublisher.gobics.de/subtinteract/interactionList/2/TrpE TrpE] | ||
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|colspan="2" style="background:#FAF8CC;" align="center"| '''Metabolic function and regulation of this protein in [[SubtiPathways|''Subti''Pathways]]: <br/>[http://subtiwiki.uni-goettingen.de/pathways/phenyl_tyr_tryp.html Phe, Tyr, Trp]''' | |colspan="2" style="background:#FAF8CC;" align="center"| '''Metabolic function and regulation of this protein in [[SubtiPathways|''Subti''Pathways]]: <br/>[http://subtiwiki.uni-goettingen.de/pathways/phenyl_tyr_tryp.html Phe, Tyr, Trp]''' |
Revision as of 19:41, 31 July 2011
- Description: anthranilate synthase (subunit I)
Gene name | trpE |
Synonyms | |
Essential | no |
Product | anthranilate synthase (subunit I) |
Function | biosynthesis of tryptophan |
Interactions involving this protein in SubtInteract: TrpE | |
Metabolic function and regulation of this protein in SubtiPathways: Phe, Tyr, Trp | |
MW, pI | 57 kDa, 5.246 |
Gene length, protein length | 1545 bp, 515 aa |
Immediate neighbours | trpD, aroH |
Get the DNA and protein sequences (Barbe et al., 2009) | |
Genetic context This image was kindly provided by SubtiList
|
Contents
Categories containing this gene/protein
biosynthesis/ acquisition of amino acids
This gene is a member of the following regulons
The gene
Basic information
- Locus tag: BSU22680
Phenotypes of a mutant
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity: Chorismate + L-glutamine = anthranilate + pyruvate + L-glutamate (according to Swiss-Prot)
- Protein family:
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity: subject to feedback inhibtion by tryptophan PubMed
- Localization:
Database entries
- UniProt: P03963
- KEGG entry: [3]
- E.C. number: 4.1.3.27
Additional information
Expression and regulation
- Operon:
- Regulatory mechanism:
- Additional information:
- subject to feedback inhibtion by tryptophan PubMed
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
Reviews
The trpE RNA switch
Other original publications