Difference between revisions of "McpB"

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* '''Description:''' methyl-accepting chemotaxis protein, receptor for asparagine <br/><br/>
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* '''Description:''' membrane-bound chemotaxis receptor, methyl-accepting chemotaxis protein, receptor for asparagine <br/><br/>
  
 
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=== Additional information===
 
=== Additional information===
 
 
  
  
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* '''Protein family:'''
 
* '''Protein family:'''
  
* '''Paralogous protein(s):'''
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* '''Paralogous protein(s):''' [[McpA]]
  
 
=== Extended information on the protein ===
 
=== Extended information on the protein ===

Revision as of 10:43, 26 April 2011

  • Description: membrane-bound chemotaxis receptor, methyl-accepting chemotaxis protein, receptor for asparagine

Gene name mcpB
Synonyms
Essential no
Product methyl-accepting chemotaxis protein
Function control of chemotaxis
MW, pI 71 kDa, 5.13
Gene length, protein length 1986 bp, 662 aa
Immediate neighbours tlpA, tgl
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
McpB context.gif
This image was kindly provided by SubtiList





Categories containing this gene/protein

motility and chemotaxis, membrane proteins

This gene is a member of the following regulons

SigD regulon

The gene

Basic information

  • Locus tag: BSU31260

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family:
  • Paralogous protein(s): McpA

Extended information on the protein

  • Kinetic information: K(D) for asparagine: 14 myM PubMed
  • Domains:
  • Modification: methylated at residues Gln371, Glu630, and Glu637 PubMed
  • Cofactor(s):
  • Effectors of protein activity: asparagine (binds to the part of McpB that is exposed to the exterior) PubMed
  • Localization:
    • cell membrane PubMed
    • localized at the cell poles, but in the presence of high asparagine concentration there is a reversible re-localization to the sides of the cell (lateral clusters) PubMed

Database entries

  • Structure:
  • KEGG entry: [3]
  • E.C. number:

Additional information

Expression and regulation

  • Regulation:
  • Regulatory mechanism:
  • Additional information:
    • in minimal medium, McpB is present with 6,200 +/- 1,900 molecules per cell PubMed

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References