Difference between revisions of "YjbH"
Line 76: | Line 76: | ||
* '''Cofactor(s):'''contains Zn atoms (coordinated by the N-terminal His-rich region) [http://www.ncbi.nlm.nih.gov/sites/entrez/19074380 PubMed] | * '''Cofactor(s):'''contains Zn atoms (coordinated by the N-terminal His-rich region) [http://www.ncbi.nlm.nih.gov/sites/entrez/19074380 PubMed] | ||
− | * '''Effectors of protein activity:''' Zn atom is released upon treatment with strong oxidants [http://www.ncbi.nlm.nih.gov/sites/entrez/19074380 PubMed] | + | * '''Effectors of protein activity:''' |
+ | ** Zn atom is released upon treatment with strong oxidants [http://www.ncbi.nlm.nih.gov/sites/entrez/19074380 PubMed] | ||
+ | ** interaction with [[YirB]] inhibits the formation of a complex with [[Spx]] {{PubMed|21378193}} | ||
− | * '''Interactions:''' YjbH-[[Spx]] [http://www.ncbi.nlm.nih.gov/sites/entrez/19074380 PubMed] | + | * '''Interactions:''' |
+ | ** [[YjbH]]-[[Spx]] [http://www.ncbi.nlm.nih.gov/sites/entrez/19074380 PubMed] | ||
+ | ** [[YirB]]-[[YjbH]] {{PubMed|21378193}} | ||
* '''Localization:''' cytosolic protein | * '''Localization:''' cytosolic protein | ||
Line 131: | Line 135: | ||
=References= | =References= | ||
− | ==Reviews== | + | ==Reviews: {{PubMed|19609260}}== |
− | + | ||
==Original Publications== | ==Original Publications== | ||
− | <pubmed>17293416 | + | '''Additional publications:''' {{PubMed|21378193}} |
+ | <pubmed>17293416, 19074380 17908206, </pubmed> | ||
[[Category:Protein-coding genes]] | [[Category:Protein-coding genes]] |
Revision as of 18:51, 28 March 2011
- Description: adaptor protein for ClpX-ClpP-catalyzed Spx degradation, confers resistance against nitrosylating agents
Gene name | yjbH |
Synonyms | |
Essential | no |
Product | adaptor protein |
Function | stimulation of Spx degradation |
MW, pI | 31 kDa, 5.206 |
Gene length, protein length | 825 bp, 275 aa |
Immediate neighbours | pepF, yjbI |
Get the DNA and protein sequences (Barbe et al., 2009) | |
Genetic context This image was kindly provided by SubtiList
|
Contents
Categories containing this gene/protein
This gene is a member of the following regulons
The gene
Basic information
- Locus tag: BSU11550
Phenotypes of a mutant
Database entries
- DBTBS entry: no entry
- SubtiList entry: [1]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity: adaptor protein for ClpX-ClpP-catalyzed Spx degradation PubMed
- Protein family: UPF0413 family (according to Swiss-Prot)
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):contains Zn atoms (coordinated by the N-terminal His-rich region) PubMed
- Effectors of protein activity:
- Localization: cytosolic protein
Database entries
- Structure:
- UniProt: O31606
- KEGG entry: [2]
- E.C. number:
Additional information
Expression and regulation
- Regulation:
- Regulatory mechanism:
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Peter Zuber, Oregon Health and Science University, USA Homepage
Claes von Wachenfeldt, Lund University, Sweden Homepage
Your additional remarks
References
Reviews: PubMed
Original Publications
Additional publications: PubMed
Saurabh K Garg, Sushma Kommineni, Luke Henslee, Ying Zhang, Peter Zuber
The YjbH protein of Bacillus subtilis enhances ClpXP-catalyzed proteolysis of Spx.
J Bacteriol: 2009, 191(4);1268-77
[PubMed:19074380]
[WorldCat.org]
[DOI]
(I p)
Jonas T Larsson, Annika Rogstam, Claes von Wachenfeldt
YjbH is a novel negative effector of the disulphide stress regulator, Spx, in Bacillus subtilis.
Mol Microbiol: 2007, 66(3);669-84
[PubMed:17908206]
[WorldCat.org]
[DOI]
(P p)
Annika Rogstam, Jonas T Larsson, Peter Kjelgaard, Claes von Wachenfeldt
Mechanisms of adaptation to nitrosative stress in Bacillus subtilis.
J Bacteriol: 2007, 189(8);3063-71
[PubMed:17293416]
[WorldCat.org]
[DOI]
(P p)