Difference between revisions of "NhaK"
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Revision as of 20:17, 2 February 2011
- Description: cation/H+ antiporter
| Gene name | nhaK |
| Synonyms | yvgP |
| Essential | no |
| Product | cation/H+ antiporter |
| Function | monovalent cation export |
| MW, pI | 75 kDa, 9.222 |
| Gene length, protein length | 2010 bp, 670 aa |
| Immediate neighbours | yvgO, cysJ |
| Get the DNA and protein sequences (Barbe et al., 2009) | |
Genetic context 
This image was kindly provided by SubtiList
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Contents
Categories containing this gene/protein
transporters/ other, metal ion homeostasis (K, Na, Ca, Mg), membrane proteins
This gene is a member of the following regulons
The gene
Basic information
- Locus tag: BSU33420
Phenotypes of a mutant
Database entries
- DBTBS entry: no entry
- SubtiList entry: [1]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity: export of Na(+), K(+), Li(+), Rb(+)
- Protein family:
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
- Interactions:
- Localization: cell membrane (according to Swiss-Prot)
Database entries
- Structure:
- UniProt: O32212
- KEGG entry: [2]
- E.C. number:
Additional information
Expression and regulation
- Regulation: constitutive, expression increases in the presence of Na(+) and K(+) PubMed
- Regulatory mechanism:
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
Makoto Fujisawa, Ayumi Kusumoto, Yuko Wada, Takahiro Tsuchiya, Masahiro Ito
NhaK, a novel monovalent cation/H+ antiporter of Bacillus subtilis.
Arch Microbiol: 2005, 183(6);411-20
[PubMed:16021482]
[WorldCat.org]
[DOI]
(P p)
