Difference between revisions of "RipX"
| Line 62: | Line 62: | ||
=== Basic information/ Evolution === | === Basic information/ Evolution === | ||
| − | * '''Catalyzed reaction/ biological activity:''' | + | * '''Catalyzed reaction/ biological activity:''' resolution of chromosome dimers by site specific recombination at the dif site (located close to the terminus region on the chromosome) |
* '''Protein family:''' XerD subfamily (according to Swiss-Prot) | * '''Protein family:''' XerD subfamily (according to Swiss-Prot) | ||
| Line 82: | Line 82: | ||
* '''Interactions:''' | * '''Interactions:''' | ||
| − | * '''Localization:''' cytoplasm (according to Swiss-Prot) | + | * '''Localization:''' |
| + | ** cytoplasm (according to Swiss-Prot) | ||
| + | ** assembles on the chromosome at the dif site throughout the cell cycle {{PubMed|21239579}} | ||
=== Database entries === | === Database entries === | ||
| Line 128: | Line 130: | ||
=References= | =References= | ||
| − | <pubmed>10498718,16597952,11208805,, </pubmed> | + | <pubmed>10498718,16597952,11208805, 21239579, </pubmed> |
[[Category:Protein-coding genes]] | [[Category:Protein-coding genes]] | ||
Revision as of 10:32, 19 January 2011
- Description: site-specific integrase/recombinase
| Gene name | ripX |
| Synonyms | ykqM |
| Essential | no |
| Product | site-specific integrase/recombinase |
| Function | chromosome partitioning |
| MW, pI | 33 kDa, 10 |
| Gene length, protein length | 888 bp, 296 aa |
| Immediate neighbours | drm, fur |
| Get the DNA and protein sequences (Barbe et al., 2009) | |
Genetic context 
This image was kindly provided by SubtiList
| |
Contents
Categories containing this gene/protein
This gene is a member of the following regulons
The gene
Basic information
- Locus tag: BSU23510
Phenotypes of a mutant
Database entries
- DBTBS entry: no entry
- SubtiList entry: [1]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity: resolution of chromosome dimers by site specific recombination at the dif site (located close to the terminus region on the chromosome)
- Protein family: XerD subfamily (according to Swiss-Prot)
- Paralogous protein(s): CodV
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
- Interactions:
- Localization:
- cytoplasm (according to Swiss-Prot)
- assembles on the chromosome at the dif site throughout the cell cycle PubMed
Database entries
- Structure:
- UniProt: P46352
- KEGG entry: [2]
- E.C. number:
Additional information
Expression and regulation
- Operon:
- Regulation:
- Regulatory mechanism:
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
Christine Kaimer, Katrin Schenk, Peter L Graumann
Two DNA translocases synergistically affect chromosome dimer resolution in Bacillus subtilis.
J Bacteriol: 2011, 193(6);1334-40
[PubMed:21239579]
[WorldCat.org]
[DOI]
(I p)
Alexandra E Bloor, Rocky M Cranenburgh
An efficient method of selectable marker gene excision by Xer recombination for gene replacement in bacterial chromosomes.
Appl Environ Microbiol: 2006, 72(4);2520-5
[PubMed:16597952]
[WorldCat.org]
[DOI]
(P p)
S A Sciochetti, P J Piggot, G W Blakely
Identification and characterization of the dif Site from Bacillus subtilis.
J Bacteriol: 2001, 183(3);1058-68
[PubMed:11208805]
[WorldCat.org]
[DOI]
(P p)
S A Sciochetti, P J Piggot, D J Sherratt, G Blakely
The ripX locus of Bacillus subtilis encodes a site-specific recombinase involved in proper chromosome partitioning.
J Bacteriol: 1999, 181(19);6053-62
[PubMed:10498718]
[WorldCat.org]
[DOI]
(P p)
