Difference between revisions of "SubtInteract"
| Line 14: | Line 14: | ||
'''Attention:''' Each technique detects only about 33% of all interactions {{PubMed|20805792,19060903}} | '''Attention:''' Each technique detects only about 33% of all interactions {{PubMed|20805792,19060903}} | ||
| − | == | + | ==Vizualisation of protein-protein interactions in ''B. subtilis''== |
* the beta version of an interactive protein-protein interaction map [http://cellpublisher.gobics.de/subtinteract/interactionList/PtsH here] (just replace "PtsH" in the browser line by the protein of your interest) | * the beta version of an interactive protein-protein interaction map [http://cellpublisher.gobics.de/subtinteract/interactionList/PtsH here] (just replace "PtsH" in the browser line by the protein of your interest) | ||
* the beta version of [http://subtiwiki.uni-goettingen.de/pathways/SubtInteract/demo_mitlinks/ SubtInteract] | * the beta version of [http://subtiwiki.uni-goettingen.de/pathways/SubtInteract/demo_mitlinks/ SubtInteract] | ||
| + | ==Protein complexes in ''B. subtilis''== | ||
| + | * [[DNA replication]]: the [[replisome]] | ||
| + | * [[transcription]]: [[RNA polymerase]] | ||
| + | * [[translation]]: the [[ribosome]] | ||
| + | * [[cell division]]: the [[divisome]] | ||
| + | |||
| + | * [[metabolism]]: the metabolons of glycolysis and the TCA cycle {{PubMed|19193632,20933603}} | ||
==Important publications== | ==Important publications== | ||
<pubmed>20658969 18228443 18219467 17953394 15264234 14706816 12127457 11827824 11377797 11306254 10851163 10842303 18366733 10694888 2200717 2441660 </pubmed> | <pubmed>20658969 18228443 18219467 17953394 15264234 14706816 12127457 11827824 11377797 11306254 10851163 10842303 18366733 10694888 2200717 2441660 </pubmed> | ||
Revision as of 21:43, 3 January 2011
Protein-protein interactions are essential for many activities of any living cell. These interactions involve multi-protein complexes that take part in central processes such as DNA replication, transcription or translation. Protein-protein interactions may also be involved in a variety of regulatory events. Metabolic enzymes do often form transien complexes that represent a complete pathways. These complexes are called metabolon. Finally, many interactions may be of a transient nature.
Contents
Methods to detect protein-protein interactions
- Yeast Two Hybrid System PubMed
- TAP-Tag purification PubMed
Attention: Each technique detects only about 33% of all interactions PubMed
Vizualisation of protein-protein interactions in B. subtilis
- the beta version of an interactive protein-protein interaction map here (just replace "PtsH" in the browser line by the protein of your interest)
- the beta version of SubtInteract
Protein complexes in B. subtilis
- cell division: the divisome
- metabolism: the metabolons of glycolysis and the TCA cycle PubMed
Important publications
