SecY

• Description: preprotein translocase subunit, universally conserved protein
  
  

Gene name	secY
Synonyms
Essential	yes PubMed
Product	preprotein translocase subunit
Function	protein secretion
Metabolic function and regulation of this protein in SubtiPathways: Protein secretion
MW, pI	47 kDa, 10.209
Gene length, protein length	1293 bp, 431 aa
Immediate neighbours	rplO, adk
Get the DNA and protein sequences (Barbe et al., 2009)
Genetic context This image was kindly provided by SubtiList

Categories containing this gene/protein

protein secretion, essential genes, membrane proteins, universally conserved proteins

This gene is a member of the following regulons

stringent response

The gene

Basic information

• Locus tag: BSU01360

Phenotypes of a mutant

essential PubMed

Database entries

• DBTBS entry: no entry

• SubtiList entry: [1]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity:

• Protein family: secY/SEC61-alpha family (according to Swiss-Prot)

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions: (SecY-SecE-SecG)2-SecA2 PubMed

• Localization: membrane PubMed

Database entries

• Structure: 3DL8 (structure of the (SecY-SecE-SecG)-SecA complex PubMed

• UniProt: P16336

• KEGG entry: [2]

• E.C. number:

Additional information

universally conserved protein

Expression and regulation

• Operon: rplO-secY-adk-map

• Sigma factor:

• Regulation:
  • RelA dependent downregulation (Class I) during stringent response PubMed

• Regulatory mechanism:

• Additional information:

Biological materials

• Mutant: Pspac-secY PubMed

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody: