Difference between revisions of "MurP"

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|style="background:#ABCDEF;" align="center"|'''Function''' || N-acetyl muramic acid uptake and phosphorylation
 
|style="background:#ABCDEF;" align="center"|'''Function''' || N-acetyl muramic acid uptake and phosphorylation
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|colspan="2" style="background:#FAF8CC;" align="center"| '''Metabolic function and regulation of this protein in [[SubtiPathways|''Subti''Pathways]]: <br/>[http://subtiwiki.uni-goettingen.de/pathways/murein/index.html Murein recycling]'''
 
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|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 47 kDa, 8.496   
 
|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 47 kDa, 8.496   

Revision as of 13:23, 11 December 2010

Gene name murP
Synonyms ybbF
Essential no
Product N-acetyl muramic acid-specific
phosphotransferase system, EIIBC component
Function N-acetyl muramic acid uptake and phosphorylation
Metabolic function and regulation of this protein in SubtiPathways:
Murein recycling
MW, pI 47 kDa, 8.496
Gene length, protein length 1365 bp, 455 aa
Immediate neighbours amiE, murR
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
YbbF context.gif
This image was kindly provided by SubtiList






Categories containing this gene/protein

cell wall degradation/ turnover, phosphotransferase systems, utilization of specific carbon sources, phosphoproteins

This gene is a member of the following regulons

The gene

Basic information

  • Locus tag: BSU01680

Phenotypes of a mutant

Database entries

  • DBTBS entry: no entry
  • SubtiList entry: [1]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity: transport and concomitant phosphorylation of N-acetyl muramic acid
  • Protein family: PTS permease, sucrose permease (Scr) family PubMed
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:
  • Interactions:
  • Localization:

Database entries

  • Structure:
  • KEGG entry: [2]
  • E.C. number:

Additional information

Expression and regulation

  • Operon:
  • Sigma factor:
  • Regulation:
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

Ulrike Dahl, Tina Jaeger, Bao Trâm Nguyen, Julia M Sattler, Christoph Mayer
Identification of a phosphotransferase system of Escherichia coli required for growth on N-acetylmuramic acid.
J Bacteriol: 2004, 186(8);2385-92
[PubMed:15060041] [WorldCat.org] [DOI] (P p)

Jonathan Reizer, Steffi Bachem, Aiala Reizer, Maryvonne Arnaud, Milton H Saier, Jörg Stülke
Novel phosphotransferase system genes revealed by genome analysis - the complete complement of PTS proteins encoded within the genome of Bacillus subtilis.
Microbiology (Reading): 1999, 145 ( Pt 12);3419-3429
[PubMed:10627040] [WorldCat.org] [DOI] (P p)