DEAD-box RNA helicases

Parent categories	3. Information processing 3.2. RNA synthesis and degradation
Neighbouring categories	3.2.1. Transcription 3.2.2. RNA chaperones 3.2.3. DEAD-box RNA helicases 3.2.4. RNases
Related categories	RNA chaperones
Overview on the categories (Excel file) All genes and their categories (Excel file)

Labs working on DEAD-box RNA helicases

• Dagmar Klostermeier
• Jörg Stülke
• Mohamed Marahiel

DEAD-box RNA helicases in B. subtilis

• CshA
• CshB
• DeaD
• YfmL

Strain GP1063 deleted for all four DEAD-box RNA helicases is available in Jörg Stülke's lab (cshA::aphA3 cshB::cat deaD::tet yfmL::ermC). The individual mutants are available as well.

Key reviews

Eric A Gustafson, Gary M Wessel
DEAD-box helicases: posttranslational regulation and function.
Biochem Biophys Res Commun: 2010, 395(1);1-6
[PubMed:20206133] [WorldCat.org] [DOI] (I p)

Manuel Hilbert, Anne R Karow, Dagmar Klostermeier
The mechanism of ATP-dependent RNA unwinding by DEAD box proteins.
Biol Chem: 2009, 390(12);1237-50
[PubMed:19747077] [WorldCat.org] [DOI] (I p)

Patrick Linder
Dead-box proteins: a family affair--active and passive players in RNP-remodeling.
Nucleic Acids Res: 2006, 34(15);4168-80
[PubMed:16936318] [WorldCat.org] [DOI] (I p)

Frances V Fuller-Pace
DExD/H box RNA helicases: multifunctional proteins with important roles in transcriptional regulation.
Nucleic Acids Res: 2006, 34(15);4206-15
[PubMed:16935882] [WorldCat.org] [DOI] (I p)

Olivier Cordin, Josette Banroques, N Kyle Tanner, Patrick Linder
The DEAD-box protein family of RNA helicases.
Gene: 2006, 367;17-37
[PubMed:16337753] [WorldCat.org] [DOI] (P p)

Sanda Rocak, Patrick Linder
DEAD-box proteins: the driving forces behind RNA metabolism.
Nat Rev Mol Cell Biol: 2004, 5(3);232-41
[PubMed:14991003] [WorldCat.org] [DOI] (P p)

N Kyle Tanner
The newly identified Q motif of DEAD box helicases is involved in adenine recognition.
Cell Cycle: 2003, 2(1);18-9
[PubMed:12695678] [WorldCat.org] [DOI] (P p)

Jon R Lorsch
RNA chaperones exist and DEAD box proteins get a life.
Cell: 2002, 109(7);797-800
[PubMed:12110176] [WorldCat.org] [DOI] (P p)

Additional publications: PubMed

External links

• The RNA helicase database