Difference between revisions of "HutU"

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= [[Categories]] containing this gene/protein =
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{{SubtiWiki category|[[utilization of amino acids]]}}
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= This gene is a member of the following [[regulons]] =
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{{SubtiWiki regulon|[[AbrB regulon]]}},
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{{SubtiWiki regulon|[[CcpA regulon]]}},
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{{SubtiWiki regulon|[[CodY regulon]]}},
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{{SubtiWiki regulon|[[HutP regulon]]}}
  
 
=The gene=
 
=The gene=
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= Categories containing this gene/protein =
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{{SubtiWiki category|[[utilization of amino acids]]}}
 
 
=The protein=
 
=The protein=
  

Revision as of 00:57, 9 December 2010

  • Description: urocanase

Gene name hutU
Synonyms
Essential no
Product urocanase
Function histidine utilization
Metabolic function and regulation of this protein in SubtiPathways:
His
MW, pI 60 kDa, 5.664
Gene length, protein length 1656 bp, 552 aa
Immediate neighbours hutH, hutI
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
HutU context.gif
This image was kindly provided by SubtiList







Categories containing this gene/protein

utilization of amino acids

This gene is a member of the following regulons

AbrB regulon, CcpA regulon, CodY regulon, HutP regulon

The gene

Basic information

  • Locus tag: BSU39360

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity: 3-(5-oxo-4,5-dihydro-3H-imidazol-4-yl)propanoate = urocanate + H2O (according to Swiss-Prot)
  • Protein family: urocanase family (according to Swiss-Prot)
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:
  • Interactions:
  • Localization: cytoplasm (according to Swiss-Prot)

Database entries

  • KEGG entry: [3]

Additional information

Expression and regulation

  • Regulation:
    • repressed by glucose (CcpA) PubMed
    • induced by histidine (HutP) PubMed
    • repressed during growth in the presence of branched chain amino acids (CodY) PubMed
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References