Difference between revisions of "TrxB"
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| + | = [[Categories]] containing this gene/protein = | ||
| + | {{SubtiWiki category|[[electron transport/ other]]}}, | ||
| + | {{SubtiWiki category|[[essential genes]]}} | ||
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| + | = This gene is a member of the following [[regulons]] = | ||
| + | {{SubtiWiki regulon|[[Spx regulon]]}} | ||
=The gene= | =The gene= | ||
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=The protein= | =The protein= | ||
Revision as of 23:43, 8 December 2010
- Description: thioredoxin reductase (NADPH)
| Gene name | trxB |
| Synonyms | yvcH |
| Essential | yes PubMed |
| Product | thioredoxin reductase (NADPH) |
| Function | keeps thioredoxin in the reduced state |
| MW, pI | 34 kDa, 4.99 |
| Gene length, protein length | 948 bp, 316 aa |
| Immediate neighbours | yvcI, cwlO |
| Get the DNA and protein sequences (Barbe et al., 2009) | |
Genetic context 
This image was kindly provided by SubtiList
| |
Contents
Categories containing this gene/protein
electron transport/ other, essential genes
This gene is a member of the following regulons
The gene
Basic information
- Locus tag: BSU34790
Phenotypes of a mutant
essential PubMed
Database entries
- DBTBS entry: no entry
- SubtiList entry: [1]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity: Thioredoxin + NADP+ = thioredoxin disulfide + NADPH (according to Swiss-Prot)
- Protein family: class-II pyridine nucleotide-disulfide oxidoreductase family (according to Swiss-Prot)
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
- Interactions:
- Localization: cytoplasm (according to Swiss-Prot)
Database entries
- Structure:
- UniProt: P80880
- KEGG entry: [2]
- E.C. number: 1.8.1.9
Additional information
Expression and regulation
- Operon:
- Regulation:
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
Michiko M Nakano, Ann Lin, Cole S Zuber, Kate J Newberry, Richard G Brennan, Peter Zuber
Promoter recognition by a complex of Spx and the C-terminal domain of the RNA polymerase alpha subunit.
PLoS One: 2010, 5(1);e8664
[PubMed:20084284]
[WorldCat.org]
[DOI]
(I e)
Shunji Nakano, Michiko M Nakano, Ying Zhang, Montira Leelakriangsak, Peter Zuber
A regulatory protein that interferes with activator-stimulated transcription in bacteria.
Proc Natl Acad Sci U S A: 2003, 100(7);4233-8
[PubMed:12642660]
[WorldCat.org]
[DOI]
(P p)
