Difference between revisions of "MdtR"
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| + | = [[Categories]] containing this gene/protein = | ||
| + | {{SubtiWiki category|[[transcription factors and their control]]}}, | ||
| + | {{SubtiWiki category|[[resistance against toxins/ antibiotics]]}} | ||
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| + | = This gene is a member of the following [[regulons]] = | ||
| + | {{SubtiWiki regulon|[[MdtR regulon]]}} | ||
=The gene= | =The gene= | ||
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=The protein= | =The protein= | ||
Revision as of 23:12, 8 December 2010
| Gene name | mdtR |
| Synonyms | yusO |
| Essential | no |
| Product | transcription repressor (MarR family) |
| Function | regulation of the multidrug-resistance mdtR-mdtP operon |
| MW, pI | 17 kDa, 6.376 |
| Gene length, protein length | 465 bp, 155 aa |
| Immediate neighbours | yusN, mdtP |
| Get the DNA and protein sequences (Barbe et al., 2009) | |
Genetic context 
| |
Contents
Categories containing this gene/protein
transcription factors and their control, resistance against toxins/ antibiotics
This gene is a member of the following regulons
The gene
Basic information
- Locus tag:
Phenotypes of a mutant
Database entries
- DBTBS entry: no entry
- SubtiList entry: [1]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity:
- Protein family:
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
- Interactions:
- Localization:
Database entries
- Structure: 1S3J
- UniProt: O32181
- KEGG entry: [2]
- E.C. number:
Additional information
Expression and regulation
- Regulation:
- Regulatory mechanism: repression by MdtR PubMed
- Additional information:
Biological materials
- Mutant: GP1115 (spc), available in Stülke lab
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
Ji-Yun Kim, Takashi Inaoka, Kazutaka Hirooka, Hiroshi Matsuoka, Makiko Murata, Reiko Ohki, Yoshikazu Adachi, Yasutaro Fujita, Kozo Ochi
Identification and characterization of a novel multidrug resistance operon, mdtRP (yusOP), of Bacillus subtilis.
J Bacteriol: 2009, 191(10);3273-81
[PubMed:19286808]
[WorldCat.org]
[DOI]
(I p)
