Difference between revisions of "Hmp"

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= [[Categories]] containing this gene/protein =
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{{SubtiWiki category|[[electron transport/ other]]}},
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{{SubtiWiki category|[[resistance against other toxic compounds (nitric oxide, phenolic acids, flavonoids, oxalate)]]}}
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= This gene is a member of the following [[regulons]] =
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{{SubtiWiki regulon|[[NsrR regulon]]}},
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{{SubtiWiki regulon|[[ResD regulon]]}}
  
 
=The gene=
 
=The gene=
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= Categories containing this gene/protein =
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{{SubtiWiki category|[[electron transport/ other]]}},
 
{{SubtiWiki category|[[resistance against other toxic compounds (nitric oxide, phenolic acids, flavonoids, oxalate)]]}}
 
 
=The protein=
 
=The protein=
  

Revision as of 18:51, 8 December 2010

  • Description: flavohemoglobin, involved in resistance to nitric oxide (NO), essential for long-term survival under anaerobic conditions

Gene name hmp
Synonyms ykiA
Essential no
Product flavohemoglobin
Function resistance to NO
Metabolic function and regulation of this protein in SubtiPathways:
Stress
MW, pI 44 kDa, 5.705
Gene length, protein length 1197 bp, 399 aa
Immediate neighbours ykhA, ykzH
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
Hmp context.gif
This image was kindly provided by SubtiList







Categories containing this gene/protein

electron transport/ other, resistance against other toxic compounds (nitric oxide, phenolic acids, flavonoids, oxalate)

This gene is a member of the following regulons

NsrR regulon, ResD regulon

The gene

Basic information

  • Locus tag: BSU13040

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity: 2 NO + 2 O2 + NAD(P)H = 2 NO3- + NAD(P)+ (according to Swiss-Prot)
  • Protein family: FAD-binding FR-type domain (according to Swiss-Prot)
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:
  • Interactions:
  • Localization:

Database entries

  • Structure:
  • KEGG entry: [3]
  • E.C. number:

Additional information

Expression and regulation

  • Regulation:
    • expressed under anaerobic conditions (ResD) PubMed
    • induced by nitric oxide under anaerobic conditions (NsrR) PubMed
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References