Difference between revisions of "RsbR"

From SubtiWiki
Jump to: navigation, search
Line 32: Line 32:
  
 
<br/><br/><br/><br/><br/><br/>
 
<br/><br/><br/><br/><br/><br/>
 +
 +
= [[Categories]] containing this gene/protein =
 +
{{SubtiWiki category|[[sigma factors and their control]]}},
 +
{{SubtiWiki category|[[phosphoproteins]]}}
 +
 +
= This gene is a member of the following [[regulons]] =
 +
  
 
=The gene=
 
=The gene=
Line 51: Line 58:
  
  
= Categories containing this gene/protein =
+
 
{{SubtiWiki category|[[sigma factors and their control]]}},
 
{{SubtiWiki category|[[phosphoproteins]]}}
 
 
=The protein=
 
=The protein=
  

Revision as of 16:58, 8 December 2010

  • Description: activator of RsbT kinase activity, part of the stressosome

Gene name rsbR
Synonyms ycxR, rsbRA
Essential no
Product activator of RsbT kinase activity
Function control of SigB activity
Metabolic function and regulation of this protein in SubtiPathways:
Stress
MW, pI 30 kDa, 4.731
Gene length, protein length 822 bp, 274 aa
Immediate neighbours ndoA, rsbS
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
RsbR context.gif
This image was kindly provided by SubtiList







Categories containing this gene/protein

sigma factors and their control, phosphoproteins

This gene is a member of the following regulons

The gene

Basic information

  • Locus tag: BSU04670

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family:

Extended information on the protein

  • Kinetic information:
  • Domains: RsbRA is composed of an N-terminal nonheme globin domain and a highly conserved C-terminal STAS (Sulphate Transporter and AntiSigma factor antagonist) domain. The C-terminal STAS domain is the target of the serine/threonine-specific kinase RsbT (see below).
  • Modification: RsbRA: Thr-171 and Thr-205

phosphorylation on Thr-171 (RsbRA) PubMed

  • Cofactor(s):
  • Effectors of protein activity:
  • Localization:

Database entries

  • Structure: 2BNL (N-terminal domain), 3VY9 (complete stressosome)
  • KEGG entry: [3]
  • E.C. number:

Additional information

Expression and regulation

  • Regulation: constitutively expressed PubMed
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

Reviews


Original Articles

Additional publications: PubMed