BsaA

• Description: similar to glutathione peroxidase
  
  

Gene name	bsaA
Synonyms
Essential	no
Product	unknown
Function	unknown
MW, pI	18 kDa, 5.251
Gene length, protein length	480 bp, 160 aa
Immediate neighbours	ypgQ, metA
Get the DNA and protein sequences (Barbe et al., 2009)
Genetic context This image was kindly provided by SubtiList

The gene

Basic information

• Locus tag: BSU21900

Database entries

• DBTBS entry: no entry

• SubtiList entry: [1]

Categories containing this gene/protein

resistance against oxidative and electrophile stress

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity:

• Protein family:

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:

• Localization:

Database entries

• Structure:

• UniProt: P52035

• KEGG entry: [2]

• E.C. number:

Additional information

The gene is annotated in KEGG as glutathione peroxidase EC 1.11.1.9. It is marked in Swiss-Prot as “glutathione peroxidase homolog” and in MetaCyc as “glutathione peroxidase”. Several studies suggested that glutathione is probably absent in B. subtilis. PubMed

Expression and regulation

• Operon:

• Sigma factor:

• Regulation:

• Regulatory mechanism:

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody:

References

Tzu-Lin Hsiao, Olga Revelles, Lifeng Chen, Uwe Sauer, Dennis Vitkup
Automatic policing of biochemical annotations using genomic correlations.
Nat Chem Biol: 2010, 6(1);34-40
[PubMed:19935659] [WorldCat.org] [DOI] (I p)

V Capuano, N Galleron, P Pujic, A Sorokin, S D Ehrlich
Organization of the Bacillus subtilis 168 chromosome between kdg and the attachment site of the SP beta prophage: use of Long Accurate PCR and yeast artificial chromosomes for sequencing.
Microbiology (Reading): 1996, 142 ( Pt 11);3005-15
[PubMed:8969496] [WorldCat.org] [DOI] (P p)