Difference between revisions of "Fin"
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* '''Description:''' | * '''Description:''' | ||
| − | ** suppressor of ''[[recU]]'' mutations, participates in the stabilization and or processing of holliday junction intermediates {{PubMed|11810266}} | + | ** suppressor of ''[[recU]]'' mutations, participates in the stabilization and or processing of holliday junction intermediates {{PubMed|11810266}}<br/> |
** alternative description: antagonist to [[SigF]], required for the switch from [[SigF]]- to [[SigG]]-dependent gene expression in the forespore {{PubMed|21037003}}<br/><br/> | ** alternative description: antagonist to [[SigF]], required for the switch from [[SigF]]- to [[SigG]]-dependent gene expression in the forespore {{PubMed|21037003}}<br/><br/> | ||
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===Phenotypes of a mutant === | ===Phenotypes of a mutant === | ||
| − | + | sporulation defect (50-fold reduction of viable spore count) and arrest after engulfment {{PubMed|21037003}} | |
=== Database entries === | === Database entries === | ||
Revision as of 17:08, 3 November 2010
- Description:
| Gene name | subA |
| Synonyms | yabK |
| Essential | no |
| Product | unknown |
| Function | homologous recombination |
| MW, pI | 8 kDa, 5.192 |
| Gene length, protein length | 228 bp, 76 aa |
| Immediate neighbours | spoVC, mfd |
| Get the DNA and protein sequences (Barbe et al., 2009) | |
Genetic context 
This image was kindly provided by SubtiList
| |
Contents
The gene
Basic information
- Locus tag: BSU00540
Phenotypes of a mutant
sporulation defect (50-fold reduction of viable spore count) and arrest after engulfment PubMed
Database entries
- DBTBS entry: no entry
- SubtiList entry: [1]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity:
- Protein family:
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
- Localization: localizes diffusely within the forespore compartment of sporangia at both early and late stages of sporulation, cytosolic protein PubMed
Database entries
- Structure:
- UniProt: P37553
- KEGG entry: [2]
- E.C. number:
Additional information
Expression and regulation
- Operon:
- Regulation: expressed in two waves in the forespore (after two hours (SigF) and three hours (SigG) after the onset of sporulation) PubMed
- Regulatory mechanism:
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
Begoña Carrasco, M Castillo Cozar, Rudi Lurz, Juan C Alonso, Silvia Ayora
Genetic recombination in Bacillus subtilis 168: contribution of Holliday junction processing functions in chromosome segregation.
J Bacteriol: 2004, 186(17);5557-66
[PubMed:15317759]
[WorldCat.org]
[DOI]
(P p)
B Carrasco, S Fernández, K Asai, N Ogasawara, J C Alonso
Effect of the recU suppressors sms and subA on DNA repair and homologous recombination in Bacillus subtilis.
Mol Genet Genomics: 2002, 266(5);899-906
[PubMed:11810266]
[WorldCat.org]
[DOI]
(P p)
Additional publications: PubMed
