Difference between revisions of "KinC"

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* '''Cofactor(s):'''
 
* '''Cofactor(s):'''
  
* '''Effectors of protein activity:''' activity is triggered by potassium leakage {{PubMed|19114652}}
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* '''Effectors of protein activity:'''  
 
+
** activity is triggered by potassium leakage {{PubMed|19114652}}
 +
** activity is triggered by polyisoprenoid lipids formed by [[YisP]] {{PubMed|20713508}}
 +
 
* '''Interactions:''' [[KinC]]-[[Spo0A]] {{PubMed|19114652}}, [[KinC]]-[[Spo0F]]
 
* '''Interactions:''' [[KinC]]-[[Spo0A]] {{PubMed|19114652}}, [[KinC]]-[[Spo0F]]
  
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=References=
 
=References=
  
<pubmed>19114652,10094672,11069677,16166384,,8002615, 16479537 8002614 </pubmed>
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<pubmed>19114652,10094672,11069677,16166384, 20713508,8002615, 16479537 8002614 </pubmed>
  
 
[[Category:Protein-coding genes]]
 
[[Category:Protein-coding genes]]

Revision as of 16:05, 14 October 2010

Gene name kinC
Synonyms ssb
Essential no
Product two-component sensor kinase
Function initiation of sporulation
Function and regulation of this protein in SubtiPathways:
Phosphorelay
MW, pI 48 kDa, 6.225
Gene length, protein length 1284 bp, 428 aa
Immediate neighbours abh, ykqA
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
KinC context.gif
This image was kindly provided by SubtiList







The gene

Basic information

  • Locus tag: BSU14490

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity: autophosphorylation, phosphorylation of Spo0F as part of the phosphorelay, but also direct phosphorylation of Spo0A PubMed
  • Protein family:
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains: two transmembrane segments, C-terminal histidine phosphotransferase domain
  • Modification: autophosphorylation on a His residue
  • Cofactor(s):
  • Effectors of protein activity:
    • activity is triggered by potassium leakage PubMed
    • activity is triggered by polyisoprenoid lipids formed by YisP PubMed
  • Localization: cell membrane (Heterogeneous) PubMed

Database entries

  • Structure:
  • KEGG entry: [3]
  • E.C. number:

Additional information

Expression and regulation

  • Operon: kinC (according to DBTBS)
  • Regulation:
    • expressed under conditions that trigger sporulation (Spo0A) PubMed
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References