Difference between revisions of "MccA"
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* '''Regulatory mechanism:''' | * '''Regulatory mechanism:''' | ||
** [[CymR]]: transcription repression [http://www.ncbi.nlm.nih.gov/sites/entrez/16513748 PubMed] | ** [[CymR]]: transcription repression [http://www.ncbi.nlm.nih.gov/sites/entrez/16513748 PubMed] | ||
− | ** [[Spx]]: transcription activation {{PubMed|12642660}} | + | ** [[Spx]]: transcription activation {{PubMed|12642660,16885442}} |
* '''Additional information:''' | * '''Additional information:''' | ||
Line 123: | Line 123: | ||
=References= | =References= | ||
− | <pubmed>17056751,16513748,, 12642660, </pubmed> | + | <pubmed>17056751,16513748,16885442, 12642660, </pubmed> |
[[Category:Protein-coding genes]] | [[Category:Protein-coding genes]] |
Revision as of 17:00, 8 October 2010
- Description: O-acetylserine-thiol-lyase
Gene name | mccA |
Synonyms | yrhA |
Essential | no |
Product | O-acetylserine-thiol-lyase |
Function | methionine-to-cysteine conversion |
Metabolic function and regulation of this protein in SubtiPathways: Cys, Met & Sulfate assimilation | |
MW, pI | 32 kDa, 5.227 |
Gene length, protein length | 921 bp, 307 aa |
Immediate neighbours | mccB, mtnN |
Get the DNA and protein sequences (Barbe et al., 2009) | |
Genetic context This image was kindly provided by SubtiList
|
Contents
The gene
Basic information
- Locus tag: BSU27260
Phenotypes of a mutant
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity: O(3)-acetyl-L-serine + L-homocysteine = L-cystathionine + acetate (according to Swiss-Prot)
- Protein family: cysteine synthase/cystathionine beta-synthase family (according to Swiss-Prot)
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
- Interactions:
- Localization:
Database entries
- Structure:
- UniProt: O05393
- KEGG entry: [3]
- E.C. number:
Additional information
Expression and regulation
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References