Difference between revisions of "CtaO"

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(Basic information/ Evolution)
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* '''Regulatory mechanism:'''  
 
* '''Regulatory mechanism:'''  
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** [[AbrB]]: transcription repression {{PubMed|20817675}}
  
 
* '''Additional information:'''  
 
* '''Additional information:'''  
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=References=
 
=References=
  
<pubmed>10675592,, </pubmed>
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<pubmed>10675592,20817675, </pubmed>
  
 
[[Category:Protein-coding genes]]
 
[[Category:Protein-coding genes]]

Revision as of 19:21, 15 September 2010

  • Description: heme O synthase (minor enzyme)

Gene name ctaO
Synonyms yjdK
Essential no
Product heme O synthase (minor enzyme)
Function heme biosynthesis
MW, pI 36 kDa, 10.121
Gene length, protein length 987 bp, 329 aa
Immediate neighbours yjdJ, cotT
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
CtaO context.gif
This image was kindly provided by SubtiList




The gene

Basic information

  • Locus tag: BSU12080

Phenotypes of a mutant

Database entries

  • DBTBS entry: no entry
  • SubtiList entry: [1]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family: Protoheme IX farnesyltransferase subfamily (according to Swiss-Prot)
  • Paralogous protein(s): CtaB

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:
  • Interactions:
  • Localization: cell membrane (according to Swiss-Prot)

Database entries

  • Structure:
  • KEGG entry: [2]
  • E.C. number:

Additional information

Expression and regulation

  • Operon:
  • Regulation:
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

Onuma Chumsakul, Hiroki Takahashi, Taku Oshima, Takahiro Hishimoto, Shigehiko Kanaya, Naotake Ogasawara, Shu Ishikawa
Genome-wide binding profiles of the Bacillus subtilis transition state regulator AbrB and its homolog Abh reveals their interactive role in transcriptional regulation.
Nucleic Acids Res: 2011, 39(2);414-28
[PubMed:20817675] [WorldCat.org] [DOI] (I p)

M Throne-Holst, L Hederstedt
The Bacillus subtilis ctaB paralogue, yjdK, can complement the heme A synthesis deficiency of a CtaB-deficient mutant.
FEMS Microbiol Lett: 2000, 183(2);247-51
[PubMed:10675592] [WorldCat.org] [DOI] (P p)