Difference between revisions of "TkmA"
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===Phenotypes of a mutant === | ===Phenotypes of a mutant === | ||
| − | + | the mutant exhibits a defect in biofilm formation {{PubMed|20815827}} | |
=== Database entries === | === Database entries === | ||
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=Expression and regulation= | =Expression and regulation= | ||
| + | * '''Operon:''' ''[[tkmA]]-[[ptkA]]-[[ptpZ]]-[[ugd]]'' {{PubMed|20815827,12970183}} | ||
| − | * | + | * '''[[Sigma factor]]:''' [[SigA]] {{PubMed|20815827}} |
| − | |||
| − | |||
* '''Regulation:''' | * '''Regulation:''' | ||
* '''Regulatory mechanism:''' | * '''Regulatory mechanism:''' | ||
| + | ** [[DegU]]-P: transcription repression {{PubMed|20815827}} | ||
* '''Additional information:''' | * '''Additional information:''' | ||
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=References= | =References= | ||
| − | <pubmed>12970183, </pubmed> | + | <pubmed>12970183, 20815827 </pubmed> |
[[Category:Protein-coding genes]] | [[Category:Protein-coding genes]] | ||
Revision as of 09:25, 13 September 2010
- Description: transmembrane modulator of PtkA activity, activates PtkA autophosphorylation and substrate phosphorylation
| Gene name | tkmA |
| Synonyms | ywqC |
| Essential | no |
| Product | modulator of PtkA activity |
| Function | control of protein tyrosine phosphorylation |
| MW, pI | 26 kDa, 4.61 |
| Gene length, protein length | 744 bp, 248 aa |
| Immediate neighbours | ptkA, ywqB |
| Get the DNA and protein sequences (Barbe et al., 2009) | |
Genetic context 
This image was kindly provided by SubtiList
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Contents
The gene
Basic information
- Locus tag: BSU36260
Phenotypes of a mutant
the mutant exhibits a defect in biofilm formation PubMed
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity: transmembrane activation of PtkA protein tyrosine kinase activity
- Protein family: cpsC/capA family (according to Swiss-Prot)
- Paralogous protein(s): EpsA
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
- Localization: cell membrane (according to Swiss-Prot)
Database entries
- Structure:
- UniProt: P96715
- KEGG entry: [3]
- E.C. number:
Additional information
Expression and regulation
- Regulation:
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
