Difference between revisions of "DacB"

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(Database entries)
(Database entries)
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=== Database entries ===
 
=== Database entries ===
  
* '''Structure:''' [http://www.pdb.org/pdb/explore/explore.do?structureId=3MFD 3MFD]
+
* '''Structure:''' [http://www.pdb.org/pdb/explore/explore.do?structureId=3MFD 3MFD] (beta-lactamase superfamily domain)
  
 
* '''UniProt:''' [http://www.uniprot.org/uniprot/P35150 P35150]
 
* '''UniProt:''' [http://www.uniprot.org/uniprot/P35150 P35150]

Revision as of 13:47, 24 August 2010

Gene name dacB
Synonyms
Essential no
Product penicillin-binding protein 5, D-alanyl-D-alanine carboxypeptidase
Function carboxypeptidase
MW, pI 42 kDa, 9.725
Gene length, protein length 1146 bp, 382 aa
Immediate neighbours spmA, ypuI
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
DacB context.gif
This image was kindly provided by SubtiList



The gene

Basic information

  • Locus tag: BSU23190

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity: Preferential cleavage: (Ac)(2)-L-Lys-D-Ala-|-D-Ala (according to Swiss-Prot)
  • Protein family: peptidase S11 family (according to Swiss-Prot)
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:
  • Interactions:
  • Localization: cell membrane (according to Swiss-Prot)

Database entries

  • Structure: 3MFD (beta-lactamase superfamily domain)
  • KEGG entry: [3]
  • E.C. number:

Additional information

Expression and regulation

  • Regulation:
    • expressed early during sporulation in the mother cell (SigE) PubMed
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References