Difference between revisions of "MciZ"
| Line 54: | Line 54: | ||
=== Basic information/ Evolution === | === Basic information/ Evolution === | ||
| − | * '''Catalyzed reaction/ biological activity:''' | + | * '''Catalyzed reaction/ biological activity:''' inhibits GTPase activity of [[FtsZ]] and Z ring formation during sporulation {{PubMed|18284588}} |
* '''Protein family:''' | * '''Protein family:''' | ||
| Line 72: | Line 72: | ||
* '''Effectors of protein activity:''' | * '''Effectors of protein activity:''' | ||
| − | * '''Interactions:''' [[MciZ]]-[[FtsZ]] | + | * '''Interactions:''' [[MciZ]]-[[FtsZ]] {{PubMed|18284588}} |
* '''Localization:''' | * '''Localization:''' | ||
| Line 92: | Line 92: | ||
* '''Operon:''' | * '''Operon:''' | ||
| − | * '''[[Sigma factor]]:''' | + | * '''[[Sigma factor]]:''' [[SigE]] {{PubMed|18284588}} |
* '''Regulation:''' | * '''Regulation:''' | ||
| + | ** expressed early during sporulation in the mother cell ([[SigE]]) {{PubMed|18284588}} | ||
* '''Regulatory mechanism:''' | * '''Regulatory mechanism:''' | ||
Revision as of 08:22, 8 August 2010
- Description: FtsZ inhibition peptide
| Gene name | mciZ |
| Synonyms | |
| Essential | no |
| Product | FtsZ inhibition peptide |
| Function | inhibits GTPase activity of FtsZ and Z ring formation during sporulation |
| MW, pI | 4.8 kDa, y.yy |
| Gene length, protein length | 120 bp, 40 aa |
| Immediate neighbours | nudF, yqkF |
| Gene sequence (+200bp) | Protein sequence |
Genetic context 
This image was kindly provided by SubtiList
| |
Contents
The gene
Basic information
- Locus tag:
Phenotypes of a mutant
Database entries
- DBTBS entry: no entry
- SubtiList entry: no entry
Additional information
This gene was only recently identified. PubMed
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity: inhibits GTPase activity of FtsZ and Z ring formation during sporulation PubMed
- Protein family:
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
- Localization:
Database entries
- Structure:
- Swiss prot entry:
- KEGG entry: no entry
- E.C. number:
Additional information
Expression and regulation
- Operon:
- Regulatory mechanism:
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
Reviews
David W Adams, Jeff Errington
Bacterial cell division: assembly, maintenance and disassembly of the Z ring.
Nat Rev Microbiol: 2009, 7(9);642-53
[PubMed:19680248]
[WorldCat.org]
[DOI]
(I p)
Original Publications
Aaron A Handler, Joo Eun Lim, Richard Losick
Peptide inhibitor of cytokinesis during sporulation in Bacillus subtilis.
Mol Microbiol: 2008, 68(3);588-99
[PubMed:18284588]
[WorldCat.org]
[DOI]
(I p)
