Difference between revisions of "MenC"

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(Your additional remarks)
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* '''Description:''' O-succinylbenzoate-CoA synthase <br/><br/>
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* '''Description:''' O-succinylbenzoate synthase <br/><br/>
  
 
{| align="right" border="1" cellpadding="2"  
 
{| align="right" border="1" cellpadding="2"  
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|style="background:#ABCDEF;" align="center"| '''Essential''' || yes [http://www.ncbi.nlm.nih.gov/pubmed/12682299 PubMed]  
 
|style="background:#ABCDEF;" align="center"| '''Essential''' || yes [http://www.ncbi.nlm.nih.gov/pubmed/12682299 PubMed]  
 
|-
 
|-
|style="background:#ABCDEF;" align="center"| '''Product''' || O-succinylbenzoate-CoA synthase
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|style="background:#ABCDEF;" align="center"| '''Product''' || O-succinylbenzoate synthase
 
|-
 
|-
 
|style="background:#ABCDEF;" align="center"|'''Function''' || biosynthesis of menaquinone  
 
|style="background:#ABCDEF;" align="center"|'''Function''' || biosynthesis of menaquinone  
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=Your additional remarks=
 
=Your additional remarks=
Shouldn't the activity/description of MenC be O-succinylbenzoate synthase rather than O-succinylbenzoate-CoA synthase?  See {{PubMed|10194342}} 10194342.
 
  
 
=References=
 
=References=
<pubmed> 9387221,1629163,8550504</pubmed>
+
<pubmed> 9387221,1629163,8550504 10194342</pubmed>
 
[[Category:Protein-coding genes]]
 
[[Category:Protein-coding genes]]

Revision as of 19:59, 13 July 2010

  • Description: O-succinylbenzoate synthase

Gene name menC
Synonyms ytfD
Essential yes PubMed
Product O-succinylbenzoate synthase
Function biosynthesis of menaquinone
Metabolic function and regulation of this protein in SubtiPathways:
Menaquinone
MW, pI 41 kDa, 5.888
Gene length, protein length 1113 bp, 371 aa
Immediate neighbours mntA, menE
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
MenC context.gif
This image was kindly provided by SubtiList







The gene

Basic information

  • Locus tag: BSU30780

Phenotypes of a mutant

essential PubMed

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity: (1R,6R)-6-hydroxy-2-succinylcyclohexa-2,4-diene-1-carboxylate = 2-succinylbenzoate + H2O (according to Swiss-Prot)
  • Protein family: mandelate racemase/muconate lactonizing enzyme family (according to Swiss-Prot)
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:
  • Interactions:
  • Localization:

Database entries

  • Structure:
  • KEGG entry: [3]

Additional information

Expression and regulation

  • Regulation:
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References