KamA

• Description: lysine 2,3-aminomutase
  
  

Gene name	kamA
Synonyms	yodO
Essential	no
Product	lysine 2,3-aminomutase
Function	lysine degradation
MW, pI	53 kDa, 6.04
Gene length, protein length	1413 bp, 471 aa
Immediate neighbours	yozE, yodP
Get the DNA and protein sequences (Barbe et al., 2009)
Genetic context This image was kindly provided by SubtiList

The gene

Basic information

• Locus tag: BSU19690

Database entries

• DBTBS entry: no entry

• SubtiList entry: [1]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity: L-lysine = (3S)-3,6-diaminohexanoate (according to Swiss-Prot)

• Protein family: UPF0720 family (according to Swiss-Prot)

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:

• Localization:

Database entries

• Structure:

• UniProt: O34676

• KEGG entry: [2]

• E.C. number: 5.4.3.2

Expression and regulation

• Operon:

• Sigma factor:

• Regulation:

• Regulatory mechanism:

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody:

References

D Chen, F J Ruzicka, P A Frey
A novel lysine 2,3-aminomutase encoded by the yodO gene of bacillus subtilis: characterization and the observation of organic radical intermediates.
Biochem J: 2000, 348 Pt 3(Pt 3);539-49
[PubMed:10839984] [WorldCat.org] (P p)