Difference between revisions of "Thi-box"
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| − | controls expression of the ''[[tenA]]-[[tenI]]-[[thiO]]-[[thiS]]-[[thiG]]-[[thiF]]-[[thiD]]'' and ''[[thiU]]-[[thiV]]-[[thiW]]-[[thiX]]'' operons as well as of the ''[[thiC]]'', ''[[thiT]]'', and ''[[ylmB]]'' genes in response to thiamine. Thiamine pyrophosphate binds the Thi-box resulting in reduced expression. | + | A [[riboswitch]] that controls the expression of the ''[[tenA]]-[[tenI]]-[[thiO]]-[[thiS]]-[[thiG]]-[[thiF]]-[[thiD]]'' and ''[[thiU]]-[[thiV]]-[[thiW]]-[[thiX]]'' operons as well as of the ''[[thiC]]'', ''[[thiT]]'', and ''[[ylmB]]'' genes in response to thiamine. Thiamine pyrophosphate binds the Thi-box resulting in reduced expression. |
<pubmed>16356850 12376536 </pubmed> | <pubmed>16356850 12376536 </pubmed> | ||
Revision as of 19:04, 12 June 2010
Important Reviews
A riboswitch that controls the expression of the tenA-tenI-thiO-thiS-thiG-thiF-thiD and thiU-thiV-thiW-thiX operons as well as of the thiC, thiT, and ylmB genes in response to thiamine. Thiamine pyrophosphate binds the Thi-box resulting in reduced expression.
Narasimhan Sudarsan, Smadar Cohen-Chalamish, Shingo Nakamura, Gail Mitchell Emilsson, Ronald R Breaker
Thiamine pyrophosphate riboswitches are targets for the antimicrobial compound pyrithiamine.
Chem Biol: 2005, 12(12);1325-35
[PubMed:16356850]
[WorldCat.org]
[DOI]
(P p)
Dmitry A Rodionov, Alexey G Vitreschak, Andrey A Mironov, Mikhail S Gelfand
Comparative genomics of thiamin biosynthesis in procaryotes. New genes and regulatory mechanisms.
J Biol Chem: 2002, 277(50);48949-59
[PubMed:12376536]
[WorldCat.org]
[DOI]
(P p)
