Difference between revisions of "Noc"
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=Expression and regulation= | =Expression and regulation= | ||
| − | + | * '''Operon:''' ''[[thdF]]-[[gidA]]-[[rsmG]]-[[noc]]'' {{PubMed|11807071}} | |
| − | * '''Operon:''' ''[[thdF]]-[[gidA]]-[[rsmG]]-[[noc]]'' | ||
* '''[[Sigma factor]]:''' | * '''[[Sigma factor]]:''' | ||
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* '''Regulatory mechanism:''' | * '''Regulatory mechanism:''' | ||
| + | ** ComK: transcription activation {{PubMed|11948146}} | ||
* '''Additional information:''' | * '''Additional information:''' | ||
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=References= | =References= | ||
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==Reviews== | ==Reviews== | ||
<pubmed> 19680248 19884039 </pubmed> | <pubmed> 19680248 19884039 </pubmed> | ||
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==Original Publications== | ==Original Publications== | ||
| − | <pubmed>16549676,11807071,19494834,15210112,, </pubmed> | + | <pubmed>16549676,11807071,19494834,15210112,11948146 , </pubmed> |
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[[Category:Protein-coding genes]] | [[Category:Protein-coding genes]] | ||
Revision as of 11:38, 13 February 2010
- Description: DNA-binding protein, spatial regulator of cell division to protect the nucleoid, and timing device with an important role in the coordination of chromosome segregation and cell division
| Gene name | noc |
| Synonyms | yyaA |
| Essential | no |
| Product | effector of nucleoid occlusion |
| Function | control of cell division |
| MW, pI | 32 kDa, 5.812 |
| Gene length, protein length | 849 bp, 283 aa |
| Immediate neighbours | yyaB, rsmG |
| Get the DNA and protein sequences (Barbe et al., 2009) | |
Genetic context 
This image was kindly provided by SubtiList
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Contents
The gene
Basic information
- Locus tag: BSU40990
Phenotypes of a mutant
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity: binds specific sites on the chromosome PubMed
- Protein family: ParB family (according to Swiss-Prot)
- Paralogous protein(s): Spo0J
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
- Interactions:
- Localization: cytoplasm (according to Swiss-Prot)
Database entries
- Structure:
- UniProt: P37524
- KEGG entry: [3]
- E.C. number:
Additional information
Expression and regulation
- Regulation:
- Regulatory mechanism:
- ComK: transcription activation PubMed
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion: available in the Jeff Errington lab
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Jeff Errington, Newcastle, UK Homepage
Your additional remarks
References
Reviews
Marc Bramkamp, Suey van Baarle
Division site selection in rod-shaped bacteria.
Curr Opin Microbiol: 2009, 12(6);683-8
[PubMed:19884039]
[WorldCat.org]
[DOI]
(I p)
David W Adams, Jeff Errington
Bacterial cell division: assembly, maintenance and disassembly of the Z ring.
Nat Rev Microbiol: 2009, 7(9);642-53
[PubMed:19680248]
[WorldCat.org]
[DOI]
(I p)
Original Publications
