Difference between revisions of "ThiG"
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* '''Effectors of protein activity:''' | * '''Effectors of protein activity:''' | ||
| − | * '''Interactions:''' [[ThiS]]-[[ThiG]] | + | * '''Interactions:''' [[ThiS]]-[[ThiG]] {{PubMed|15362849}} |
* '''Localization:''' cytoplasm (according to Swiss-Prot) | * '''Localization:''' cytoplasm (according to Swiss-Prot) | ||
| Line 76: | Line 76: | ||
=== Database entries === | === Database entries === | ||
| − | * '''Structure:''' [http://www.rcsb.org/pdb/explore.do?structureId=1XM3 1XM3], | + | * '''Structure:''' [http://www.rcsb.org/pdb/explore.do?structureId=1XM3 1XM3], [http://www.rcsb.org/pdb/explore/explore.do?structureId=1TYG 1TYG] (complex with [[ThiG]]) {{PubMed|15362849}} |
* '''UniProt:''' [http://www.uniprot.org/uniprot/O31618 O31618] | * '''UniProt:''' [http://www.uniprot.org/uniprot/O31618 O31618] | ||
Revision as of 15:58, 3 February 2010
- Description: hydroxyethylthiazole phosphate biosynthesis
| Gene name | thiG |
| Synonyms | yjbT |
| Essential | no |
| Product | thiamin thiazole synthase |
| Function | biosynthesis of thiamine |
| MW, pI | 26 kDa, 4.718 |
| Gene length, protein length | 768 bp, 256 aa |
| Immediate neighbours | thiS, thiF |
| Get the DNA and protein sequences (Barbe et al., 2009) | |
Genetic context 
This image was kindly provided by SubtiList
| |
Contents
The gene
Basic information
- Locus tag: BSU11690
Phenotypes of a mutant
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity:
- Protein family: thiG family (according to Swiss-Prot)
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Cofactor(s):
- Effectors of protein activity:
- Localization: cytoplasm (according to Swiss-Prot)
Database entries
- UniProt: O31618
- KEGG entry: [3]
- E.C. number:
Additional information
Expression and regulation
- Regulatory mechanism:
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
Reviews
Christopher T Jurgenson, Tadhg P Begley, Steven E Ealick
The structural and biochemical foundations of thiamin biosynthesis.
Annu Rev Biochem: 2009, 78;569-603
[PubMed:19348578]
[WorldCat.org]
[DOI]
(I p)
Original publications
