Rho

• Description: transcriptional termination protein
  
  

Gene name	rho
Synonyms
Essential	no
Product	transcriptional termination protein
Function	transcriptional termination
MW, pI	48 kDa, 6.865
Gene length, protein length	1281 bp, 427 aa
Immediate neighbours	rpmE, glpX
Get the DNA and protein sequences (Barbe et al., 2009)
Genetic context This image was kindly provided by SubtiList

The gene

Basic information

• Locus tag: BSU37080

Database entries

• DBTBS entry: no entry

• SubtiList entry: [1]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity:

• Protein family: rho family (according to Swiss-Prot)

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:

• Localization:

Database entries

• Structure:

• UniProt: Q03222

• KEGG entry: [2]

• E.C. number:

Expression and regulation

• Operon:

• Sigma factor:

• Regulation:

• Regulatory mechanism:

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody:

References

Reviews

M Sofia Ciampi
Rho-dependent terminators and transcription termination.
Microbiology (Reading): 2006, 152(Pt 9);2515-2528
[PubMed:16946247] [WorldCat.org] [DOI] (P p)

John P Richardson
Loading Rho to terminate transcription.
Cell: 2003, 114(2);157-9
[PubMed:12887917] [WorldCat.org] [DOI] (P p)

J P Richardson
Structural organization of transcription termination factor Rho.
J Biol Chem: 1996, 271(3);1251-4
[PubMed:8576105] [WorldCat.org] [DOI] (P p)

Original publications

Vitaly Epshtein, Dipak Dutta, Joseph Wade, Evgeny Nudler
An allosteric mechanism of Rho-dependent transcription termination.
Nature: 2010, 463(7278);245-9
[PubMed:20075920] [WorldCat.org] [DOI] (I p)

H Yakhnin, J E Babiarz, A V Yakhnin, P Babitzke
Expression of the Bacillus subtilis trpEDCFBA operon is influenced by translational coupling and Rho termination factor.
J Bacteriol: 2001, 183(20);5918-26
[PubMed:11566991] [WorldCat.org] [DOI] (P p)

C J Ingham, J Dennis, P A Furneaux
Autogenous regulation of transcription termination factor Rho and the requirement for Nus factors in Bacillus subtilis.
Mol Microbiol: 1999, 31(2);651-63
[PubMed:10027981] [WorldCat.org] [DOI] (P p)