Difference between revisions of "TasA"

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(Expression and regulation)
Line 98: Line 98:
  
 
* '''Regulatory mechanism:'''  
 
* '''Regulatory mechanism:'''  
** [[SinR]]: transcription repression [http://www.ncbi.nlm.nih.gov/sites/entrez/16430695 PubMed]
 
 
** [[AbrB]]:  transcription repression [http://www.ncbi.nlm.nih.gov/sites/entrez/10464223,17720793 PubMed]
 
** [[AbrB]]:  transcription repression [http://www.ncbi.nlm.nih.gov/sites/entrez/10464223,17720793 PubMed]
** [[SlrR]]: transcription activation {{PubMed|18647168}}  
+
** [[SinR]]: transcription repression {{PubMed|16430695}}
  
 
* '''Additional information:'''  
 
* '''Additional information:'''  
** induction by sequestration of [[SinR]] by [[SinI]] {{PubMed|15661000}}
+
** induction by sequestration of [[SinR]] by [[SinI]] or [[SlrA]] {{PubMed|15661000,19788541}}
** activation by [[SlrR]] requires prior formation of the [[SlrR]]-[[SlrA]] complex {{PubMed|18647168}}
 
  
 
=Biological materials =
 
=Biological materials =

Revision as of 10:09, 30 December 2009

  • Description: major component of biofilm matrix, translocation-dependent antimicrobial spore component

Gene name tasA
Synonyms cotN, yqhF
Essential no
Product major component of biofilm matrix
Function biofilm formation
MW, pI 28 kDa, 5.442
Gene length, protein length 783 bp, 261 aa
Immediate neighbours sinR, sipW
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
TasA context.gif
This image was kindly provided by SubtiList



The gene

Basic information

  • Locus tag: BSU24620

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family: peptidase M73 family (according to Swiss-Prot)
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:
  • Interactions:
  • Localization: extracellular (signal peptide) PubMed, membrane PubMed

Database entries

  • Structure:
  • KEGG entry: [3]
  • E.C. number:

Additional information

Expression and regulation

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References