Difference between revisions of "SdpR"
| Line 68: | Line 68: | ||
* '''Cofactor(s):''' | * '''Cofactor(s):''' | ||
| − | * '''Effectors of protein activity:''' | + | * '''Effectors of protein activity:''' [[SdpI]] binds and sequesters [[SdpR]] if extracellular [[SdpC]] is present, this results in induction of the ''[[sdpR]]-[[sdpI]]'' operon {{PubMed|16469701}} |
| − | * '''Interactions:''' | + | * '''Interactions:''' [[SdpI]]-[[SdpR]] {{PubMed|16469701}} |
* '''Localization:''' cytoplasm (according to Swiss-Prot) | * '''Localization:''' cytoplasm (according to Swiss-Prot) | ||
| Line 87: | Line 87: | ||
=Expression and regulation= | =Expression and regulation= | ||
| − | + | * '''Operon:''' ''[[sdpR]]-[[sdpI]]'' {{PubMed|12817086}} | |
| − | * '''Operon:''' | + | |
| − | + | * '''[[Sigma factor]]:''' [[SigA]] {{PubMed|16469701}} | |
| − | * '''[[Sigma factor]]:''' | ||
* '''Regulation:''' | * '''Regulation:''' | ||
| − | ** repressed during logrithmic growth ([[AbrB]]) [ | + | ** repressed during logrithmic growth ([[AbrB]]) {{PubMed|16469701}} |
| + | ** induced by extracellular [[SdpC]] ([[SdpR]]) {{PubMed|16469701}} | ||
* '''Regulatory mechanism:''' | * '''Regulatory mechanism:''' | ||
| − | ** [[AbrB]]: transcription repression [ | + | ** [[AbrB]]: transcription repression {{PubMed|16469701}} |
| + | ** [[SdpR]]: transcription repression {{PubMed|16469701}} | ||
* '''Additional information:''' | * '''Additional information:''' | ||
| Line 120: | Line 121: | ||
=References= | =References= | ||
| − | <pubmed>12817086,16469701,10960106,, | + | <pubmed>12817086,16469701,10960106,,, </pubmed> |
[[Category:Protein-coding genes]] | [[Category:Protein-coding genes]] | ||
Revision as of 10:48, 29 December 2009
| Gene name | sdpR |
| Synonyms | yvbA |
| Essential | no |
| Product | transcriptional regulator (ArsR family) |
| Function | regulation of protection against SdpC |
| MW, pI | 10 kDa, 7.328 |
| Gene length, protein length | 270 bp, 90 aa |
| Immediate neighbours | sdpI, opuCD |
| Get the DNA and protein sequences (Barbe et al., 2009) | |
Genetic context 
This image was kindly provided by SubtiList
| |
Contents
The gene
Basic information
- Locus tag: BSU33790
Phenotypes of a mutant
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity:
- Protein family:
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity: SdpI binds and sequesters SdpR if extracellular SdpC is present, this results in induction of the sdpR-sdpI operon PubMed
- Localization: cytoplasm (according to Swiss-Prot)
Database entries
- Structure:
- UniProt: O32242
- KEGG entry: [3]
- E.C. number:
Additional information
Expression and regulation
- Regulation:
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
Craig D Ellermeier, Errett C Hobbs, Jose E Gonzalez-Pastor, Richard Losick
A three-protein signaling pathway governing immunity to a bacterial cannibalism toxin.
Cell: 2006, 124(3);549-59
[PubMed:16469701]
[WorldCat.org]
[DOI]
(P p)
José E González-Pastor, Errett C Hobbs, Richard Losick
Cannibalism by sporulating bacteria.
Science: 2003, 301(5632);510-3
[PubMed:12817086]
[WorldCat.org]
[DOI]
(I p)
M S Turner, J D Helmann
Mutations in multidrug efflux homologs, sugar isomerases, and antimicrobial biosynthesis genes differentially elevate activity of the sigma(X) and sigma(W) factors in Bacillus subtilis.
J Bacteriol: 2000, 182(18);5202-10
[PubMed:10960106]
[WorldCat.org]
[DOI]
(P p)
