Difference between revisions of "CadA"
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=Expression and regulation= | =Expression and regulation= | ||
− | * '''Operon:''' | + | * '''Operon:''' ''cadA'' {{PubMed|12779235}} |
− | * '''[[Sigma factor]]:''' | + | * '''[[Sigma factor]]:''' [[SigA]] {{PubMed|12779235}} |
* '''Regulation:''' | * '''Regulation:''' | ||
− | ** | + | ** induced by toxic metal ions (Zn(II), Cd(II), Co(II), Ni(II) and Cu(II)) ([[CzrA]]) {{PubMed|12779235,15948947}} |
* '''Regulatory mechanism:''' | * '''Regulatory mechanism:''' | ||
− | ** [[CzrA]]: transcription repression | + | ** [[CzrA]]: transcription repression {{PubMed|15948947}} |
− | * '''Additional information:''' | + | * '''Additional information:''' |
=Biological materials = | =Biological materials = |
Revision as of 08:34, 29 December 2009
- Description: cadmium transporting ATPase, resistance to cadmium
Gene name | cadA |
Synonyms | yvgW |
Essential | no |
Product | cadmium transporting ATPase |
Function | cadmium export |
MW, pI | 75 kDa, 5.998 |
Gene length, protein length | 2106 bp, 702 aa |
Immediate neighbours | bdbD, copA |
Get the DNA and protein sequences (Barbe et al., 2009) | |
Genetic context This image was kindly provided by SubtiList
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Contents
The gene
Basic information
- Locus tag: BSU33490
Phenotypes of a mutant
Database entries
- DBTBS entry: no entry
- SubtiList entry: [1]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity: ATP + H2O + Cd2+(In) = ADP + phosphate + Cd2+(Out) (according to Swiss-Prot)
- Protein family: Type IB subfamily (according to Swiss-Prot)
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
- Interactions:
- Localization: cell membrane (according to Swiss-Prot)
Database entries
- Structure:
- UniProt: O32219
- KEGG entry: [2]
- E.C. number: 3.6.3.3
Additional information
Expression and regulation
- Operon: cadA PubMed
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
John Helmann, Cornell University, USA Homepage
Your additional remarks
References