Difference between revisions of "PucR"

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* '''Description:''' transcriptional regulator of puc genes <br/><br/>
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* '''Description:''' transcriptional regulator of ''puc'' genes <br/><br/>
  
 
{| align="right" border="1" cellpadding="2"  
 
{| align="right" border="1" cellpadding="2"  
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|style="background:#ABCDEF;" align="center"| '''Essential''' || no  
 
|style="background:#ABCDEF;" align="center"| '''Essential''' || no  
 
|-
 
|-
|style="background:#ABCDEF;" align="center"| '''Product''' || transcriptional regulator of puc genes
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|style="background:#ABCDEF;" align="center"| '''Product''' || transcriptional regulator of ''puc'' genes
 
|-
 
|-
 
|style="background:#ABCDEF;" align="center"|'''Function''' || regulation of purine utilization
 
|style="background:#ABCDEF;" align="center"|'''Function''' || regulation of purine utilization
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=Expression and regulation=
 
=Expression and regulation=
  
* '''Operon:'''  
+
* '''Operon:''' ''[[pucR]]-[[pucJ]]-[[pucK]]-[[pucL]]-[[pucM]]'' {{PubMed|12029039}}
  
* '''[[Sigma factor]]:'''  
+
* '''[[Sigma factor]]:''' [[SigA]] {{PubMed|12029039}}
  
* '''Regulation:''' negative autoregulation [http://www.ncbi.nlm.nih.gov/sites/entrez/12029039 PubMed]
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* '''Regulation:'''  
 +
** negative autoregulation {{PubMed|12029039}}
  
* '''Regulatory mechanism:''' repression by '''PucR''' [http://www.ncbi.nlm.nih.gov/sites/entrez/12029039 PubMed]
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* '''Regulatory mechanism:'''  
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** repression by '''PucR''' {{PubMed|12029039}}
  
 
* '''Additional information:'''
 
* '''Additional information:'''

Revision as of 15:07, 28 December 2009

  • Description: transcriptional regulator of puc genes

Gene name pucR
Synonyms yunI
Essential no
Product transcriptional regulator of puc genes
Function regulation of purine utilization
Metabolic function and regulation of this protein in SubtiPathways:
Nucleotides (regulation)
MW, pI 60 kDa, 6.188
Gene length, protein length 1593 bp, 531 aa
Immediate neighbours pucH, pucJ
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
PucR context.gif
This image was kindly provided by SubtiList







The gene

Basic information

  • Locus tag: BSU32420

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family: cdaR family (according to Swiss-Prot)
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:
  • Interactions:
  • Localization:

Database entries

  • Structure:
  • KEGG entry: [3]
  • E.C. number:

Additional information

Expression and regulation

  • Regulation:
    • negative autoregulation PubMed
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References