Difference between revisions of "SppA"
| Line 87: | Line 87: | ||
=Expression and regulation= | =Expression and regulation= | ||
| + | * '''Operon:''' ''[[sppA]]-[[yteJ]]'' {{PubMed|9987136}} | ||
| − | * ''' | + | * '''Sigma factor:''' [[SigW]] {{PubMed|9987136,12207695}} |
| − | |||
| − | |||
* '''Regulation:''' | * '''Regulation:''' | ||
| + | ** induced in response to cell wall stress ([[SigW]]) {{PubMed|12207695}} | ||
* '''Regulatory mechanism:''' | * '''Regulatory mechanism:''' | ||
| Line 118: | Line 118: | ||
=References= | =References= | ||
| − | <pubmed>9987136, | + | <pubmed>9987136,12207695 </pubmed> |
[[Category:Protein-coding genes]] | [[Category:Protein-coding genes]] | ||
Revision as of 08:28, 19 December 2009
- Description: signal peptide peptidase required for efficient processing of pre-proteins
| Gene name | sppA |
| Synonyms | yteI |
| Essential | no |
| Product | signal peptide peptidase |
| Function | protein secretion |
| MW, pI | 36 kDa, 7.314 |
| Gene length, protein length | 1005 bp, 335 aa |
| Immediate neighbours | yteJ, ytdI |
| Get the DNA and protein sequences (Barbe et al., 2009) | |
Genetic context 
This image was kindly provided by SubtiList
| |
Contents
The gene
Basic information
- Locus tag: BSU29530
Phenotypes of a mutant
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity:
- Protein family: peptidase S49 family (according to Swiss-Prot)
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
- Interactions:
- Localization: cell membrane (according to Swiss-Prot)
Database entries
- Structure:
- UniProt: O34525
- KEGG entry: [3]
- E.C. number:
Additional information
Expression and regulation
- Regulatory mechanism:
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
Min Cao, Tao Wang, Rick Ye, John D Helmann
Antibiotics that inhibit cell wall biosynthesis induce expression of the Bacillus subtilis sigma(W) and sigma(M) regulons.
Mol Microbiol: 2002, 45(5);1267-76
[PubMed:12207695]
[WorldCat.org]
[DOI]
(P p)
X Huang, A Gaballa, M Cao, J D Helmann
Identification of target promoters for the Bacillus subtilis extracytoplasmic function sigma factor, sigma W.
Mol Microbiol: 1999, 31(1);361-71
[PubMed:9987136]
[WorldCat.org]
[DOI]
(P p)
