Difference between revisions of "RNA switch"

Revision as of 20:14, 17 December 2009

RNA switches are regulatory systems that rely on alternative mRNA structures.

RNA switches may be triggered by proteins, tRNAs (T-box), or metabolites (riboswitches)

Protein-dependent RNA switches
- L20 leader: in front of the infC-rpmI-rplT-ysdA operon: controlled by RplT binding
- ptsG-ptsH-ptsI: controlled by GlcT
- sacX-sacY, sacB: controlled by SacY
- sacP-sacA: controlled by SacT
- bglS, bglP-bglH-yxiE: controlled by BglP
- glpD, glpF-glpK, glpT-glpQ: controlled by GlpP
- pabA, trpE-trpD-trpC-trpF-trpB-trpA, trpP, ycbK: controlled by MtrB
- hutH-hutU-hutI-hutG-hutM: controlled by HutP
- pyrR-pyrP-pyrB-pyrC-pyrAA-pyrAB-pyrK-pyrD-pyrF-pyrE: PyrR

Riboswitches
- A-box
- FMN-box
- G-box
- Gly-box
- L-box
- M-box
- preQ1 riboswitch
- ribozyme: glmS
- S-box
- Thi-box

The function of these potential RNA structures is unknown. They were suggested to control the mentioned genes.

@@ Line 10: / Line 10: @@
 ** ''[[sacX]]-[[sacY]]'', ''[[sacB]]'': controlled by [[SacY]]
 ** ''[[sacP]]-[[sacA]]'': controlled by [[SacT]]
-** ''[[bglS]]'', ''[[bglP]]-[[bglH]]'': controlled by [[BglP]]
+** ''[[bglS]]'', ''[[bglP]]-[[bglH]]-[[yxiE]]'': controlled by [[BglP]]
+** ''[[glpD]]'', ''[[glpF]]-[[glpK]]'', ''[[glpT]]-[[glpQ]]'': controlled by [[GlpP]]
+** ''[[pabA]]'', ''[[trpE]]-[[trpD]]-[[trpC]]-[[trpF]]-[[trpB]]-[[trpA]]'', ''[[trpP]]'', ''[[ycbK]]'': controlled by [[TRAP|MtrB]]
+** ''[[hutH]]-[[hutU]]-[[hutI]]-[[hutG]]-[[hutM]]'': controlled by [[HutP]]
+** ''[[pyrR]]-[[pyrP]]-[[pyrB]]-[[pyrC]]-[[pyrAA]]-[[pyrAB]]-[[pyrK]]-[[pyrD]]-[[pyrF]]-[[pyrE]]'': [[PyrR]]
 *'''[[T-box]]'''