Difference between revisions of "YclN"
| Line 1: | Line 1: | ||
| − | * '''Description:''' | + | * '''Description:''' petrobactin (3.4-cattecholate siderophore) [[ABC transporter]] (permease) <br/><br/> |
{| align="right" border="1" cellpadding="2" | {| align="right" border="1" cellpadding="2" | ||
| Line 10: | Line 10: | ||
|style="background:#ABCDEF;" align="center"| '''Essential''' || no | |style="background:#ABCDEF;" align="center"| '''Essential''' || no | ||
|- | |- | ||
| − | |style="background:#ABCDEF;" align="center"| '''Product''' || | + | |style="background:#ABCDEF;" align="center"| '''Product''' || petrobactin [[ABC transporter]] (permease) |
|- | |- | ||
| − | |style="background:#ABCDEF;" align="center"|'''Function''' || | + | |style="background:#ABCDEF;" align="center"|'''Function''' || iron acquisition |
|- | |- | ||
|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 34 kDa, 9.817 | |style="background:#ABCDEF;" align="center"| '''MW, pI''' || 34 kDa, 9.817 | ||
| Line 52: | Line 52: | ||
=== Basic information/ Evolution === | === Basic information/ Evolution === | ||
| − | * '''Catalyzed reaction/ biological activity:''' | + | * '''Catalyzed reaction/ biological activity:''' uptake of the siderophore petrobactin {{PubMed|19955416}} |
* '''Protein family:''' FecCD subfamily (according to Swiss-Prot) | * '''Protein family:''' FecCD subfamily (according to Swiss-Prot) | ||
| Line 88: | Line 88: | ||
=Expression and regulation= | =Expression and regulation= | ||
| − | * '''Operon:''' | + | * '''Operon:''' ''[[yclN]]-[[yclO]]-[[yclP]]-[[yclQ]]'' {{PubMed|19955416}} |
* '''[[Sigma factor]]:''' | * '''[[Sigma factor]]:''' | ||
* '''Regulation:''' | * '''Regulation:''' | ||
| − | ** | + | ** induced upon iron starvation ([[Fur]]) [http://www.ncbi.nlm.nih.gov/sites/entrez/12354229 PubMed] |
* '''Regulatory mechanism:''' | * '''Regulatory mechanism:''' | ||
| Line 120: | Line 120: | ||
=References= | =References= | ||
| − | <pubmed>10092453,,12354229, </pubmed> | + | <pubmed>10092453, 19955416,12354229, </pubmed> |
[[Category:Protein-coding genes]] | [[Category:Protein-coding genes]] | ||
Revision as of 09:09, 4 December 2009
- Description: petrobactin (3.4-cattecholate siderophore) ABC transporter (permease)
| Gene name | yclN |
| Synonyms | |
| Essential | no |
| Product | petrobactin ABC transporter (permease) |
| Function | iron acquisition |
| MW, pI | 34 kDa, 9.817 |
| Gene length, protein length | 948 bp, 316 aa |
| Immediate neighbours | yclM, yclO |
| Get the DNA and protein sequences (Barbe et al., 2009) | |
Genetic context 
This image was kindly provided by SubtiList
| |
Contents
The gene
Basic information
- Locus tag: BSU03800
Phenotypes of a mutant
Database entries
- DBTBS entry: no entry
- SubtiList entry: [1]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity: uptake of the siderophore petrobactin PubMed
- Protein family: FecCD subfamily (according to Swiss-Prot)
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
- Interactions:
- Localization: cell membrane (according to Swiss-Prot)
Database entries
- Structure:
- UniProt: P94418
- KEGG entry: [2]
- E.C. number:
Additional information
Expression and regulation
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
Anna M Zawadzka, Youngchang Kim, Natalia Maltseva, Rita Nichiporuk, Yao Fan, Andrzej Joachimiak, Kenneth N Raymond
Characterization of a Bacillus subtilis transporter for petrobactin, an anthrax stealth siderophore.
Proc Natl Acad Sci U S A: 2009, 106(51);21854-9
[PubMed:19955416]
[WorldCat.org]
[DOI]
(I p)
Noel Baichoo, Tao Wang, Rick Ye, John D Helmann
Global analysis of the Bacillus subtilis Fur regulon and the iron starvation stimulon.
Mol Microbiol: 2002, 45(6);1613-29
[PubMed:12354229]
[WorldCat.org]
[DOI]
(P p)
Y Quentin, G Fichant, F Denizot
Inventory, assembly and analysis of Bacillus subtilis ABC transport systems.
J Mol Biol: 1999, 287(3);467-84
[PubMed:10092453]
[WorldCat.org]
[DOI]
(P p)
