Difference between revisions of "RapG"
| Line 1: | Line 1: | ||
| − | * '''Description:''' response regulator aspartate phosphatase <br/><br/> | + | * '''Description:''' response regulator aspartate phosphatase, controls [[DegU]] activity <br/><br/> |
{| align="right" border="1" cellpadding="2" | {| align="right" border="1" cellpadding="2" | ||
| Line 12: | Line 12: | ||
|style="background:#ABCDEF;" align="center"| '''Product''' || response regulator aspartate phosphatase | |style="background:#ABCDEF;" align="center"| '''Product''' || response regulator aspartate phosphatase | ||
|- | |- | ||
| − | |style="background:#ABCDEF;" align="center"|'''Function''' || control of | + | |style="background:#ABCDEF;" align="center"|'''Function''' || control of [[DegU]] activity |
|- | |- | ||
|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 42 kDa, 4.807 | |style="background:#ABCDEF;" align="center"| '''MW, pI''' || 42 kDa, 4.807 | ||
| Line 52: | Line 52: | ||
=== Basic information/ Evolution === | === Basic information/ Evolution === | ||
| − | * '''Catalyzed reaction/ biological activity:''' | + | * '''Catalyzed reaction/ biological activity:''' control of [[DegU]] activity {{PubMed|12950930}} |
* '''Protein family:''' RAP family (according to Swiss-Prot) | * '''Protein family:''' RAP family (according to Swiss-Prot) | ||
| Line 68: | Line 68: | ||
* '''Cofactor(s):''' | * '''Cofactor(s):''' | ||
| − | * '''Effectors of protein activity:''' | + | * '''Effectors of protein activity:''' binding of [[PhrG]] to [[RapG]] prevents it from binding [[DegU]] {{PubMed|12950930}} |
| − | * '''Interactions:''' [[DegU]]-[[RapG]] | + | * '''Interactions:''' [[DegU]]-[[RapG]] {{PubMed|12950930}}, [[PhrG]]-[[RapG]] {{PubMed|12950930}} |
* '''Localization:''' | * '''Localization:''' | ||
| Line 122: | Line 122: | ||
=References= | =References= | ||
| − | <pubmed>16553878,16430695,, | + | <pubmed>16553878,16430695,,12950930 , </pubmed> |
[[Category:Protein-coding genes]] | [[Category:Protein-coding genes]] | ||
Revision as of 11:09, 29 November 2009
- Description: response regulator aspartate phosphatase, controls DegU activity
| Gene name | rapG |
| Synonyms | yycM |
| Essential | no |
| Product | response regulator aspartate phosphatase |
| Function | control of DegU activity |
| MW, pI | 42 kDa, 4.807 |
| Gene length, protein length | 1095 bp, 365 aa |
| Immediate neighbours | yycN, phrG |
| Get the DNA and protein sequences (Barbe et al., 2009) | |
Genetic context 
This image was kindly provided by SubtiList
| |
Contents
The gene
Basic information
- Locus tag: BSU40300
Phenotypes of a mutant
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Protein family: RAP family (according to Swiss-Prot)
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Localization:
Database entries
- Structure:
- UniProt: O32294
- KEGG entry: [3]
- E.C. number:
Additional information
Expression and regulation
- Operon:
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
Kentaro Hayashi, Tsukahara Kensuke, Kazuo Kobayashi, Naotake Ogasawara, Mitsuo Ogura
Bacillus subtilis RghR (YvaN) represses rapG and rapH, which encode inhibitors of expression of the srfA operon.
Mol Microbiol: 2006, 59(6);1714-29
[PubMed:16553878]
[WorldCat.org]
[DOI]
(P p)
Frances Chu, Daniel B Kearns, Steven S Branda, Roberto Kolter, Richard Losick
Targets of the master regulator of biofilm formation in Bacillus subtilis.
Mol Microbiol: 2006, 59(4);1216-28
[PubMed:16430695]
[WorldCat.org]
[DOI]
(P p)
Mitsuo Ogura, Kana Shimane, Kei Asai, Naotake Ogasawara, Teruo Tanaka
Binding of response regulator DegU to the aprE promoter is inhibited by RapG, which is counteracted by extracellular PhrG in Bacillus subtilis.
Mol Microbiol: 2003, 49(6);1685-97
[PubMed:12950930]
[WorldCat.org]
[DOI]
(P p)
