Difference between revisions of "RapD"

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* '''Description:''' response regulator aspartate phosphatase <br/><br/>
+
* '''Description:''' response regulator aspartate phosphatase, controls [[ComA]] activity <br/><br/>
  
 
{| align="right" border="1" cellpadding="2"  
 
{| align="right" border="1" cellpadding="2"  
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|style="background:#ABCDEF;" align="center"| '''Product''' || response regulator aspartate phosphatase
 
|style="background:#ABCDEF;" align="center"| '''Product''' || response regulator aspartate phosphatase
 
|-
 
|-
|style="background:#ABCDEF;" align="center"|'''Function''' || control of sporulation initiation
+
|style="background:#ABCDEF;" align="center"|'''Function''' || control of [[ComA]]-dependent gene expression
 
|-
 
|-
 
|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 41 kDa, 7.691   
 
|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 41 kDa, 7.691   
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=== Basic information/ Evolution ===
 
=== Basic information/ Evolution ===
  
* '''Catalyzed reaction/ biological activity:'''  
+
* '''Catalyzed reaction/ biological activity:''' control of [[ComA]]-dependent gene expression {{PubMed|17227471}}
  
 
* '''Protein family:''' RAP family (according to Swiss-Prot)
 
* '''Protein family:''' RAP family (according to Swiss-Prot)
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=Expression and regulation=
 
=Expression and regulation=
  
* '''Operon:'''  
+
* '''Operon:''' ''[[rapD]]'' {{PubMed|9636707}}
  
* '''[[Sigma factor]]:'''  
+
* '''[[Sigma factor]]:''' [[SigA]] {{PubMed|9636707}}, [[SigX]] {{PubMed|9636707}}
  
 
* '''Regulation:'''  
 
* '''Regulation:'''  
** repressed by [[RghR]] [http://www.ncbi.nlm.nih.gov/sites/entrez/17227471 PubMed]
+
** repressed by [[RghR]] {{PubMed|17227471}}
  
 
* '''Regulatory mechanism:'''  
 
* '''Regulatory mechanism:'''  
** [[RghR]]: transcription repression [http://www.ncbi.nlm.nih.gov/sites/entrez/17227471 PubMed]
+
** [[RghR]]: transcription repression {{PubMed|17227471}}
  
 
* '''Additional information:'''  
 
* '''Additional information:'''  
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=References=
 
=References=
  
<pubmed>17227471,9636707,,17227471, </pubmed>
+
<pubmed>17227471,9636707, </pubmed>
  
 
[[Category:Protein-coding genes]]
 
[[Category:Protein-coding genes]]

Revision as of 07:54, 29 November 2009

  • Description: response regulator aspartate phosphatase, controls ComA activity

Gene name rapD
Synonyms ywpA
Essential no
Product response regulator aspartate phosphatase
Function control of ComA-dependent gene expression
MW, pI 41 kDa, 7.691
Gene length, protein length 1062 bp, 354 aa
Immediate neighbours ywpB, flhP
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
RapD context.gif
This image was kindly provided by SubtiList



The gene

Basic information

  • Locus tag: BSU36380

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity: control of ComA-dependent gene expression PubMed
  • Protein family: RAP family (according to Swiss-Prot)
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:
  • Interactions:
  • Localization:

Database entries

  • Structure:
  • KEGG entry: [3]
  • E.C. number:

Additional information

Expression and regulation

  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

Mitsuo Ogura, Yasutaro Fujita
Bacillus subtilis rapD, a direct target of transcription repression by RghR, negatively regulates srfA expression.
FEMS Microbiol Lett: 2007, 268(1);73-80
[PubMed:17227471] [WorldCat.org] [DOI] (P p)

X Huang, J D Helmann
Identification of target promoters for the Bacillus subtilis sigma X factor using a consensus-directed search.
J Mol Biol: 1998, 279(1);165-73
[PubMed:9636707] [WorldCat.org] [DOI] (P p)