Difference between revisions of "YvrG"
| Line 1: | Line 1: | ||
| − | * '''Description:''' sensor kinase of the YvrG-YvrHb two-component system <br/><br/> | + | * '''Description:''' [[two-component systems|two-component]] sensor kinase of the [[YvrG]]-[[YvrHb]] two-component system <br/><br/> |
{| align="right" border="1" cellpadding="2" | {| align="right" border="1" cellpadding="2" | ||
| Line 10: | Line 10: | ||
|style="background:#ABCDEF;" align="center"| '''Essential''' || no | |style="background:#ABCDEF;" align="center"| '''Essential''' || no | ||
|- | |- | ||
| − | |style="background:#ABCDEF;" align="center"| '''Product''' || two-component sensor histidine kinase | + | |style="background:#ABCDEF;" align="center"| '''Product''' || [[two-component systems|two-component]] sensor histidine kinase |
|- | |- | ||
|style="background:#ABCDEF;" align="center"|'''Function''' || regulation cell surface maintenance | |style="background:#ABCDEF;" align="center"|'''Function''' || regulation cell surface maintenance | ||
Revision as of 21:17, 27 November 2009
- Description: two-component sensor kinase of the YvrG-YvrHb two-component system
| Gene name | yvrG |
| Synonyms | |
| Essential | no |
| Product | two-component sensor histidine kinase |
| Function | regulation cell surface maintenance |
| MW, pI | 66 kDa, 9.518 |
| Gene length, protein length | 1719 bp, 573 aa |
| Immediate neighbours | yvrE, yvrHb |
| Get the DNA and protein sequences (Barbe et al., 2009) | |
Genetic context 
This image was kindly provided by SubtiList
| |
Contents
The gene
Basic information
- Locus tag: BSU33210
Phenotypes of a mutant
unusual autolysis and higher susceptibility to cell envelope antibiotics (bacitracin, aztreonam, cefepime, fosfomycin) PubMed
Database entries
- DBTBS entry: no entry
- SubtiList entry: [1]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity: ATP + protein L-histidine = ADP + protein N-phospho-L-histidine (according to Swiss-Prot) phosphorylation of the YvrHb response regulator PubMed
- Protein family:
Extended information on the protein
- Kinetic information:
- Domains: two transmembrane segments, C-terminal histidine phosphotransferase domain
- Modification:
- Cofactor(s):
- Effectors of protein activity:
- Localization: cell membrane (according to Swiss-Prot)
Database entries
- Structure:
- UniProt: O34989
- KEGG entry: [2]
- E.C. number:
Additional information
Expression and regulation
- Operon:
- Sigma factor:
- Regulation:
- Regulatory mechanism:
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
Letal I Salzberg, John D Helmann
Phenotypic and transcriptomic characterization of Bacillus subtilis mutants with grossly altered membrane composition.
J Bacteriol: 2008, 190(23);7797-807
[PubMed:18820022]
[WorldCat.org]
[DOI]
(I p)
Masakuni Serizawa, Keisuke Kodama, Hiroki Yamamoto, Kazuo Kobayashi, Naotake Ogasawara, Junichi Sekiguchi
Functional analysis of the YvrGHb two-component system of Bacillus subtilis: identification of the regulated genes by DNA microarray and northern blot analyses.
Biosci Biotechnol Biochem: 2005, 69(11);2155-69
[PubMed:16306698]
[WorldCat.org]
[DOI]
(P p)
C Fabret, V A Feher, J A Hoch
Two-component signal transduction in Bacillus subtilis: how one organism sees its world.
J Bacteriol: 1999, 181(7);1975-83
[PubMed:10094672]
[WorldCat.org]
[DOI]
(P p)
