Difference between revisions of "RnhC"
| Line 1: | Line 1: | ||
| − | * '''Description:''' RNase HIII, endoribonuclease <br/><br/> | + | * '''Description:''' [[RNase]] HIII, endoribonuclease <br/><br/> |
{| align="right" border="1" cellpadding="2" | {| align="right" border="1" cellpadding="2" | ||
| Line 10: | Line 10: | ||
|style="background:#ABCDEF;" align="center"| '''Essential''' || no | |style="background:#ABCDEF;" align="center"| '''Essential''' || no | ||
|- | |- | ||
| − | |style="background:#ABCDEF;" align="center"| '''Product''' || Mg2+-dependent RNase HIII | + | |style="background:#ABCDEF;" align="center"| '''Product''' || Mg2+-dependent [[RNase]] HIII |
|- | |- | ||
|style="background:#ABCDEF;" align="center"|'''Function''' || endonucleolytic cleavage of RNA <br/>in RNA-DNA hybrid molecules | |style="background:#ABCDEF;" align="center"|'''Function''' || endonucleolytic cleavage of RNA <br/>in RNA-DNA hybrid molecules | ||
Revision as of 11:11, 3 November 2009
- Description: RNase HIII, endoribonuclease
| Gene name | rnhC |
| Synonyms | ysgB |
| Essential | no |
| Product | Mg2+-dependent RNase HIII |
| Function | endonucleolytic cleavage of RNA in RNA-DNA hybrid molecules |
| MW, pI | 33 kDa, 10.07 |
| Gene length, protein length | 939 bp, 313 aa |
| Immediate neighbours | yshA, pheT |
| Get the DNA and protein sequences (Barbe et al., 2009) | |
Genetic context 
This image was kindly provided by SubtiList
| |
Contents
The gene
Basic information
- Locus tag: BSU28620
Phenotypes of a mutant
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity: Endonucleolytic cleavage to 5'-phosphomonoester (according to Swiss-Prot)
- Protein family: RnhC subfamily (according to Swiss-Prot)
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
- Interactions:
- Localization: cytoplasm (according to Swiss-Prot)
Database entries
- Structure: 2D0B (complex with Mg2+, Geobacillus stearothermophilus , 47% identity), 2D0A (Geobacillus stearothermophilus, 47% identity)
- UniProt: P94541
- KEGG entry: [3]
- E.C. number:
Additional information
Expression and regulation
- Operon:
- Regulation:
- Regulatory mechanism:
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
