Difference between revisions of "CapB"
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* '''Regulation:''' | * '''Regulation:''' | ||
| − | * '''Regulatory mechanism:''' | + | * '''Regulatory mechanism:''' [[DegU]]-P: transcription activation [http://www.ncbi.nlm.nih.gov/sites/entrez/19734658 PubMed] |
* '''Additional information:''' The operon is not expressed in the lab strain 168 due to lack of expression of [[DegQ]] resulting in inactivity of [[DegS]] and [[DegU]] | * '''Additional information:''' The operon is not expressed in the lab strain 168 due to lack of expression of [[DegQ]] resulting in inactivity of [[DegS]] and [[DegU]] | ||
| Line 122: | Line 122: | ||
=References= | =References= | ||
| − | <pubmed>11751809,19420703, 19389763, 16233197 </pubmed> | + | <pubmed>11751809,19420703, 19389763, 16233197 19734658 </pubmed> |
[[Category:Protein-coding genes]] | [[Category:Protein-coding genes]] | ||
Revision as of 12:08, 8 September 2009
- Description: capsular polyglutamate biosynthesis
| Gene name | capB |
| Synonyms | ywsC, pgsB |
| Essential | no |
| Product | poly-gamma-glutamate synthetase |
| Function | capsule synthesis |
| MW, pI | 43 kDa, 5.073 |
| Gene length, protein length | 1179 bp, 393 aa |
| Immediate neighbours | capC, rbsR |
| Get the DNA and protein sequences (Barbe et al., 2009) | |
Genetic context 
This image was kindly provided by SubtiList
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Contents
The gene
Basic information
- Locus tag: BSU35900
Phenotypes of a mutant
no synthesis of the poly-gamma-glutamate capsule PubMed
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity: synthesis of poly-gamma-glutamate from L-Glu PubMed
- Protein family:
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
- Interactions:
- Localization:
Database entries
- Structure:
- UniProt: P96736
- KEGG entry: [3]
- E.C. number:
Additional information
Expression and regulation
- Regulation:
- Additional information: The operon is not expressed in the lab strain 168 due to lack of expression of DegQ resulting in inactivity of DegS and DegU
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
