Difference between revisions of "GlpD"
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=Expression and regulation= | =Expression and regulation= | ||
| − | * '''Operon:''' ''[[glpD]]'' | + | * '''Operon:''' ''[[glpD]]'' {{PubMed|2127799}} |
| − | * '''[[Sigma factor]]:''' [[SigA]] | + | * '''[[Sigma factor]]:''' [[SigA]] {{PubMed|1809833}} |
| − | * '''Regulation:''' repressed by glucose ([[CcpA]]) | + | * '''Regulation:''' |
| + | ** repressed by glucose ([[CcpA]]) | ||
| + | ** induced by glycerol ([[GlpP]]) {{PubMed|1809833}} | ||
| − | * '''Regulatory mechanism:''' [[CcpA]]: transcription repression | + | * '''Regulatory mechanism:''' |
| + | ** [[CcpA]]: transcription repression | ||
| + | ** [[GlpP]]: transcriptional antitermination at a [[RNA switch]] {{PubMed|1809833}} | ||
* '''Additional information:''' | * '''Additional information:''' | ||
Revision as of 19:00, 4 September 2009
- Description: glycerol-3-phosphate dehydrogenase (menaquinone 7)
| Gene name | glpD |
| Synonyms | |
| Essential | no |
| Product | glycerol-3-phosphate dehydrogenase (menaquinone 7) |
| Function | |
| MW, pI | 62 kDa, 8.002 |
| Gene length, protein length | 1665 bp, 555 aa |
| Immediate neighbours | glpK, pgcA |
| Get the DNA and protein sequences (Barbe et al., 2009) | |
Genetic context 
This image was kindly provided by SubtiList
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Contents
The gene
Basic information
- Locus tag: BSU09300
Phenotypes of a mutant
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity: sn-glycerol 3-phosphate + a quinone = glycerone phosphate + a quinol (according to Swiss-Prot)
- Protein family: FAD-dependent glycerol-3-phosphate dehydrogenase family (according to Swiss-Prot)
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s): FAD
- Effectors of protein activity:
- Interactions:
- Localization: cytoplasm (according to Swiss-Prot)
Database entries
- Structure:
- UniProt: P18158
- KEGG entry: [3]
- E.C. number: 1.1.5.3
Additional information
Expression and regulation
- Regulatory mechanism:
- CcpA: transcription repression
- GlpP: transcriptional antitermination at a RNA switch PubMed
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
