Difference between revisions of "PhrC"

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(Expression and regulation)
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* '''Operon:'''  
 
* '''Operon:'''  
 +
** ''[[rapC]]-[[phrC]]'' {{PubMed|10464187}}
 +
** ''[[phrC]]'' {{PubMed|10464187}}
  
 
* '''[[Sigma factor]]:'''  
 
* '''[[Sigma factor]]:'''  
 +
** rapC: [[SigA]] {{PubMed|10464187}}
 +
** phrC: [[SigH]] {{PubMed|10464187}}
  
* '''Regulation:''' repressed by glucose (4.5-fold) ([[CcpA]]) [http://www.ncbi.nlm.nih.gov/pubmed/12850135 PubMed] 
+
* '''Regulation:'''  
** repressed during growth in the presence of branched chain amino acids ([[CodY]]) [http://www.ncbi.nlm.nih.gov/sites/entrez/10464187 PubMed]
+
** repressed during growth in the presence of branched chain amino acids ([[CodY]]) {{PubMed|10464187}}
 +
** repressed by glucose (4.5-fold) ([[CcpA]]) [http://www.ncbi.nlm.nih.gov/pubmed/12850135 PubMed]
  
* '''Regulatory mechanism:''' [[CcpA]]: transcription repression  
+
* '''Regulatory mechanism:'''  
** [[CodY]]: transcription repression [http://www.ncbi.nlm.nih.gov/sites/entrez/10464187 PubMed]
+
** [[CodY]]: transcription repression {{PubMed|10464187}}
 +
** [[ComA]]: transcription activation {{PubMed|10464187}}
 +
** [[CcpA]]: transcription repression
  
* '''Additional information:'''  
+
* '''Additional information:'''
  
 
=Biological materials =
 
=Biological materials =

Revision as of 19:19, 19 August 2009

  • Description: phosphatase (RapC) regulator / competence and sporulation stimulating factor (CSF)

Gene name phrC
Synonyms
Essential no
Product phosphatase (RapC) regulator / competence and sporulation stimulating factor (CSF)
Function control of sporulation initiation
MW, pI 4 kDa, 8.16
Gene length, protein length 120 bp, 40 aa
Immediate neighbours rapC, yclM
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
PhrC context.gif
This image was kindly provided by SubtiList



The gene

Basic information

  • Locus tag: BSU03780

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family: phr family (according to Swiss-Prot)
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:
  • Localization:

Database entries

  • Structure:
  • KEGG entry: [3]
  • E.C. number:

Additional information

Expression and regulation

  • Regulation:
    • repressed during growth in the presence of branched chain amino acids (CodY) PubMed
    • repressed by glucose (4.5-fold) (CcpA) PubMed
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References