Difference between revisions of "GlpT"
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=Expression and regulation= | =Expression and regulation= | ||
− | * '''Operon:''' ''[[glpT]]-[[glpQ]]'' | + | * '''Operon:''' ''[[glpT]]-[[glpQ]]'' {{PubMed|8012593}} |
− | * '''[[Sigma factor]]:''' [[SigA]] | + | * '''[[Sigma factor]]:''' [[SigA]] {{PubMed|8012593}} |
* '''Regulation:''' | * '''Regulation:''' | ||
** repressed by glucose (6.2-fold) ([[CcpA]]) [http://www.ncbi.nlm.nih.gov/pubmed/12850135 PubMed] | ** repressed by glucose (6.2-fold) ([[CcpA]]) [http://www.ncbi.nlm.nih.gov/pubmed/12850135 PubMed] | ||
− | ** induced by glycerol ([[GlpP]]) | + | ** induced by glycerol ([[GlpP]]) {{PubMed|8012593}} |
− | ** | + | ** induced by phosphate limitation |
* '''Regulatory mechanism:''' | * '''Regulatory mechanism:''' | ||
** [[CcpA]]: transcription repression | ** [[CcpA]]: transcription repression | ||
− | ** [[GlpP]]: transcriptional antitermination ''via'' a protein-dependent [[RNA switch]] | + | ** [[GlpP]]: transcriptional antitermination ''via'' a protein-dependent [[RNA switch]] {{PubMed|8012593}} |
* '''Additional information:''' | * '''Additional information:''' |
Revision as of 09:14, 2 August 2009
- Description: glycerol-3-phosphate permease
Gene name | glpT |
Synonyms | ybeE |
Essential | no |
Product | glycerol-3-phosphate permease |
Function | glycerol-3-phosphate uptake |
MW, pI | 49 kDa, 9.366 |
Gene length, protein length | 1332 bp, 444 aa |
Immediate neighbours | glpQ, ybeF |
Get the DNA and protein sequences (Barbe et al., 2009) | |
Genetic context This image was kindly provided by SubtiList
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Contents
The gene
Basic information
- Locus tag: BSU02140
Phenotypes of a mutant
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity:
- Protein family: SLC37A family (according to Swiss-Prot)
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
- Interactions:
- Localization: cell membrane (according to Swiss-Prot)
Database entries
- Structure:
- UniProt: P37948
- KEGG entry: [3]
- E.C. number:
Additional information
Expression and regulation
- Regulation:
- Regulatory mechanism:
- CcpA: transcription repression
- GlpP: transcriptional antitermination via a protein-dependent RNA switch PubMed
- Additional information:
Biological materials
- Mutant: QB5437, available in the Stülke lab
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References