SpoIIIC

• Description: RNA polymerase sporulation-specific sigma factor (sigma-K) (C-terminal half), other part: spoIVCB
  
  

Gene name	spoIIIC
Synonyms	sigK, spoIVD, spoIVE
Essential	no
Product	RNA polymerase sporulation-specific sigma factor (sigma-K) (C-terminal half)
Function	late mother cell-specific gene expression
MW, pI	16 kDa, 9.608
Gene length, protein length	414 bp, 138 aa
Immediate neighbours	yqaB, yrkS
Gene sequence (+200bp)	Protein sequence
Genetic context This image was kindly provided by SubtiList

The gene

Basic information

• Locus tag: BSU26390

Database entries

• DBTBS entry: [1]

• SubtiList entry: [2]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity:

• Protein family:

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:

• Localization:

Database entries

• Structure:

• UniProt: P12254

• KEGG entry: [3]

• E.C. number:

Expression and regulation

• Operon:

• Sigma factor: SigK PubMed

• Regulation:

• Regulatory mechanism:

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody:

References

B Kunkel, R Losick, P Stragier
The Bacillus subtilis gene for the development transcription factor sigma K is generated by excision of a dispensable DNA element containing a sporulation recombinase gene.
Genes Dev: 1990, 4(4);525-35
[PubMed:2163341] [WorldCat.org] [DOI] (P p)

P Stragier, B Kunkel, L Kroos, R Losick
Chromosomal rearrangement generating a composite gene for a developmental transcription factor.
Science: 1989, 243(4890);507-12
[PubMed:2536191] [WorldCat.org] [DOI] (P p)

J Errington, S Rong, M S Rosenkrantz, A L Sonenshein
Transcriptional regulation and structure of the Bacillus subtilis sporulation locus spoIIIC.
J Bacteriol: 1988, 170(3);1162-7
[PubMed:3125151] [WorldCat.org] [DOI] (P p)

J Errington
Two separable functional domains in the sigma-subunit of RNA polymerase in Bacillus subtilis?
FEBS Lett: 1987, 224(2);257-60
[PubMed:3121385] [WorldCat.org] [DOI] (P p)

S M Turner, J Errington, J Mandelstam
Use of a lacZ gene fusion to determine the dependence pattern of sporulation operon spoIIIC in spo mutants of Bacillus subtilis: a branched pathway of expression of sporulation operons.
J Gen Microbiol: 1986, 132(11);2995-3003
[PubMed:3114422] [WorldCat.org] [DOI] (P p)