Difference between revisions of "BofC"

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Line 78: Line 78:
 
* '''Structure:''' [http://www.rcsb.org/pdb/explore.do?structureId=2BW2 2BW2]
 
* '''Structure:''' [http://www.rcsb.org/pdb/explore.do?structureId=2BW2 2BW2]
  
* '''Swiss prot entry:''' [http://www.uniprot.org/uniprot/O05391 O05391]
+
* '''UniProt:''' [http://www.uniprot.org/uniprot/O05391 O05391]
  
 
* '''KEGG entry:''' [http://www.genome.jp/dbget-bin/www_bget?bsu:BSU27750]
 
* '''KEGG entry:''' [http://www.genome.jp/dbget-bin/www_bget?bsu:BSU27750]

Revision as of 13:53, 20 July 2009

  • Description: general stress protein, controls processing of pro-SigK by SpoIVFB

Gene name bofC
Synonyms
Essential no
Product forespore regulator of the sigma-K checkpoint
Function control of processing of pro-SigK by SpoIVFB
MW, pI 19 kDa, 5.753
Gene length, protein length 510 bp, 170 aa
Immediate neighbours ruvA, csbX
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
BofC context.gif
This image was kindly provided by SubtiList



The gene

Basic information

  • Locus tag: BSU27750

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family:
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:
  • Localization:

Database entries

  • KEGG entry: [3]
  • E.C. number:

Additional information

Expression and regulation

  • Operon:
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

Stephanie T Wang, Barbara Setlow, Erin M Conlon, Jessica L Lyon, Daisuke Imamura, Tsutomu Sato, Peter Setlow, Richard Losick, Patrick Eichenberger
The forespore line of gene expression in Bacillus subtilis.
J Mol Biol: 2006, 358(1);16-37
[PubMed:16497325] [WorldCat.org] [DOI] (P p)

Hayley M Patterson, James A Brannigan, Simon M Cutting, Keith S Wilson, Anthony J Wilkinson, Eiso Ab, Tammo Diercks, Rob N de Jong, Vincent Truffault, Gert E Folkers, Robert Kaptein
The structure of bypass of forespore C, an intercompartmental signaling factor during sporulation in Bacillus.
J Biol Chem: 2005, 280(43);36214-20
[PubMed:16049010] [WorldCat.org] [DOI] (P p)

A Petersohn, M Brigulla, S Haas, J D Hoheisel, U Völker, M Hecker
Global analysis of the general stress response of Bacillus subtilis.
J Bacteriol: 2001, 183(19);5617-31
[PubMed:11544224] [WorldCat.org] [DOI] (P p)

P Wakeley, N T Hoa, S Cutting
BofC negatively regulates SpoIVB-mediated signalling in the Bacillus subtilis sigmaK-checkpoint.
Mol Microbiol: 2000, 36(6);1415-24
[PubMed:10931291] [WorldCat.org] [DOI] (P p)

Manuel Gomez, Simon M Cutting
BofC encodes a putative forespore regulator of the Bacillus subtilis sigma K checkpoint.
Microbiology (Reading): 1997, 143 ( Pt 1);157-170
[PubMed:9025289] [WorldCat.org] [DOI] (P p)