Difference between revisions of "FtsH"
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* '''Structure:''' | * '''Structure:''' | ||
| − | * ''' | + | * '''UniProt:''' [http://www.uniprot.org/uniprot/P37476 P37476] |
* '''KEGG entry:''' [http://www.genome.jp/dbget-bin/www_bget?bsu:BSU00690] | * '''KEGG entry:''' [http://www.genome.jp/dbget-bin/www_bget?bsu:BSU00690] | ||
Revision as of 09:43, 20 July 2009
- Description: ATP-dependent metalloprotease
| Gene name | ftsH |
| Synonyms | |
| Essential | no |
| Product | ATP-dependent metalloprotease |
| Function | cell division, sporulation initiation |
| Metabolic function and regulation of this protein in SubtiPathways: Stress | |
| MW, pI | 70 kDa, 5.841 |
| Gene length, protein length | 1911 bp, 637 aa |
| Immediate neighbours | hprT, coaX |
| Get the DNA and protein sequences (Barbe et al., 2009) | |
Genetic context 
This image was kindly provided by SubtiList
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Contents
The gene
Basic information
- Locus tag: BSU00690
Phenotypes of a mutant
strongly reduced sporulation frequency
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity: degrades Spo0E, resulting in reduced sporulation frequency in a ftsH mutant
- Protein family:
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
- Interactions:
- Localization: cell membrane (according to Swiss-Prot), membrane PubMed
Database entries
- Structure:
- UniProt: P37476
- KEGG entry: [3]
- E.C. number:
Additional information
Expression and regulation
- Regulation: induced by heat shock (class III)
- Regulatory mechanism:
- Additional information: the mRNA is very stable (half-life > 15 min) PubMed
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
