Difference between revisions of "LonA"
| Line 49: | Line 49: | ||
=== Additional information=== | === Additional information=== | ||
| + | A mutation in ''lonA'' suppresses the motility defect of a ''[[lytC]]'' mutant [http://www.ncbi.nlm.nih.gov/sites/entrez/19542270 PubMed] | ||
=The protein= | =The protein= | ||
| Line 120: | Line 121: | ||
=References= | =References= | ||
| − | <pubmed>7961403,7961402, </pubmed> | + | <pubmed>7961403,7961402, 19542270 </pubmed> |
Revision as of 05:59, 25 June 2009
- Description: class III heat-shock ATP-dependent protease
| Gene name | lonA |
| Synonyms | lon |
| Essential | no |
| Product | class III heat-shock ATP-dependent protease |
| Function | protein quality control |
| Regulation of this protein in SubtiPathways: Stress | |
| MW, pI | 86 kDa, 5.774 |
| Gene length, protein length | 2322 bp, 774 aa |
| Immediate neighbours | ysxC, lonB |
| Get the DNA and protein sequences (Barbe et al., 2009) | |
Genetic context 
This image was kindly provided by SubtiList
| |
Contents
The gene
Basic information
- Locus tag: BSU28200
Phenotypes of a mutant
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
A mutation in lonA suppresses the motility defect of a lytC mutant PubMed
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity: Hydrolysis of proteins in presence of ATP (according to Swiss-Prot)
- Protein family: peptidase S16 family (according to Swiss-Prot)
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
- Interactions:
- Localization:
Database entries
- Structure: 1X37 (Ssd domain)
- Swiss prot entry: P37945
- KEGG entry: [3]
- E.C. number:
Additional information
Expression and regulation
- Operon:
- Regulation:
- Regulatory mechanism:
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
Rui Chen, Sarah B Guttenplan, Kris M Blair, Daniel B Kearns
Role of the sigmaD-dependent autolysins in Bacillus subtilis population heterogeneity.
J Bacteriol: 2009, 191(18);5775-84
[PubMed:19542270]
[WorldCat.org]
[DOI]
(I p)
R Schmidt, A L Decatur, P N Rather, C P Moran, R Losick
Bacillus subtilis lon protease prevents inappropriate transcription of genes under the control of the sporulation transcription factor sigma G.
J Bacteriol: 1994, 176(21);6528-37
[PubMed:7961403]
[WorldCat.org]
[DOI]
(P p)
S Riethdorf, U Völker, U Gerth, A Winkler, S Engelmann, M Hecker
Cloning, nucleotide sequence, and expression of the Bacillus subtilis lon gene.
J Bacteriol: 1994, 176(21);6518-27
[PubMed:7961402]
[WorldCat.org]
[DOI]
(P p)
