Difference between revisions of "GlpD"
| Line 82: | Line 82: | ||
* '''Swiss prot entry:''' [http://www.uniprot.org/uniprot/P18158 P18158] | * '''Swiss prot entry:''' [http://www.uniprot.org/uniprot/P18158 P18158] | ||
| − | * '''KEGG entry:''' [http://www.genome.jp/dbget-bin/www_bget?bsu | + | * '''KEGG entry:''' [http://www.genome.jp/dbget-bin/www_bget?bsu:BSU09300] |
* '''E.C. number:''' [http://www.expasy.org/enzyme/1.1.5.3 1.1.5.3] | * '''E.C. number:''' [http://www.expasy.org/enzyme/1.1.5.3 1.1.5.3] | ||
Revision as of 02:29, 25 June 2009
- Description: glycerol-3-phosphate dehydrogenase (menaquinone 7)
| Gene name | glpD |
| Synonyms | |
| Essential | no |
| Product | glycerol-3-phosphate dehydrogenase (menaquinone 7) |
| Function | |
| MW, pI | 62 kDa, 8.002 |
| Gene length, protein length | 1665 bp, 555 aa |
| Immediate neighbours | glpK, pgcA |
| Get the DNA and protein sequences (Barbe et al., 2009) | |
Genetic context 
This image was kindly provided by SubtiList
| |
Contents
The gene
Basic information
- Locus tag: BSU09300
Phenotypes of a mutant
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity: sn-glycerol 3-phosphate + a quinone = glycerone phosphate + a quinol (according to Swiss-Prot)
- Protein family: FAD-dependent glycerol-3-phosphate dehydrogenase family (according to Swiss-Prot)
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s): FAD
- Effectors of protein activity:
- Interactions:
- Localization: cytoplasm (according to Swiss-Prot)
Database entries
- Structure:
- Swiss prot entry: P18158
- KEGG entry: [3]
- E.C. number: 1.1.5.3
Additional information
Expression and regulation
- Operon: glpD
- Regulation: repressed by glucose (CcpA)
- Regulatory mechanism: CcpA: transcription repression
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
E Glatz, A Farewell, B Rutberg
The Bacillus subtilis glpD leader and antiterminator protein GlpP provide a target for glucose repression in Escherichia coli.
FEMS Microbiol Lett: 1998, 162(1);93-6
[PubMed:9595668]
[WorldCat.org]
[DOI]
(P p)
Elisabeth Glatz, Martin Persson, Blanka Rutberg
Antiterminator protein GlpP of Bacillus subtilis binds to glpD leader mRNA.
Microbiology (Reading): 1998, 144 ( Pt 2);449-456
[PubMed:9493382]
[WorldCat.org]
[DOI]
(P p)
E Glatz, R P Nilsson, L Rutberg, B Rutberg
A dual role for the Bacillus subtilis glpD leader and the GlpP protein in the regulated expression of glpD: antitermination and control of mRNA stability.
Mol Microbiol: 1996, 19(2);319-28
[PubMed:8825777]
[WorldCat.org]
[DOI]
(P p)
C Holmberg, L Rutberg
An inverted repeat preceding the Bacillus subtilis glpD gene is a conditional terminator of transcription.
Mol Microbiol: 1992, 6(20);2931-8
[PubMed:1479885]
[WorldCat.org]
[DOI]
(P p)
