Difference between revisions of "BioB"
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* '''Swiss prot entry:''' [http://www.uniprot.org/uniprot/P53557 P53557] | * '''Swiss prot entry:''' [http://www.uniprot.org/uniprot/P53557 P53557] | ||
− | * '''KEGG entry:''' [http://www.genome.jp/dbget-bin/www_bget?bsu | + | * '''KEGG entry:''' [http://www.genome.jp/dbget-bin/www_bget?bsu:BSU30200] |
* '''E.C. number:''' [http://www.expasy.org/enzyme/2.8.1.6 2.8.1.6] | * '''E.C. number:''' [http://www.expasy.org/enzyme/2.8.1.6 2.8.1.6] |
Revision as of 01:21, 25 June 2009
- Description: biotin synthase
Gene name | bioB |
Synonyms | |
Essential | no |
Product | biotin synthase) |
Function | biosynthesis of biotin |
MW, pI | 36 kDa, 5.554 |
Gene length, protein length | 1005 bp, 335 aa |
Immediate neighbours | bioI, bioD |
Get the DNA and protein sequences (Barbe et al., 2009) | |
Genetic context This image was kindly provided by SubtiList
|
Contents
The gene
Basic information
- Locus tag: BSU30200
Phenotypes of a mutant
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity: Dethiobiotin + sulfur + 2 S-adenosyl-L-methionine = biotin + 2 L-methionine + 2 5'-deoxyadenosine (according to Swiss-Prot)
- Protein family: Biotin synthase family (according to Swiss-Prot)
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
- Interactions:
- Localization:
Database entries
- Structure:
- Swiss prot entry: P53557
- KEGG entry: [3]
- E.C. number: 2.8.1.6
Additional information
- subject to Clp-dependent proteolysis upon glucose starvation PubMed
Expression and regulation
- Operon:
- Regulation:
- Regulatory mechanism:
- Additional information: subject to Clp-dependent proteolysis upon glucose starvation PubMed
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
J B Perkins, S Bower, C L Howitt, R R Yocum, J Pero
Identification and characterization of transcripts from the biotin biosynthetic operon of Bacillus subtilis.
J Bacteriol: 1996, 178(21);6361-5
[PubMed:8892842]
[WorldCat.org]
[DOI]
(P p)
S Bower, J B Perkins, R R Yocum, C L Howitt, P Rahaim, J Pero
Cloning, sequencing, and characterization of the Bacillus subtilis biotin biosynthetic operon.
J Bacteriol: 1996, 178(14);4122-30
[PubMed:8763940]
[WorldCat.org]
[DOI]
(P p)