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− | * '''Description:''' oligopeptide ABC transporter (ATP-binding protein) <br/><br/>
| + | #REDIRECT[[appA/1]] |
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− | {| align="right" border="1" cellpadding="2"
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− | |style="background:#ABCDEF;" align="center"|'''Gene name'''
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− | |''appF''
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− | |style="background:#ABCDEF;" align="center"| '''Synonyms''' || '' ''
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− | |style="background:#ABCDEF;" align="center"| '''Essential''' || no
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− | |style="background:#ABCDEF;" align="center"| '''Product''' || oligopeptide ABC transporter (ATP-binding protein))
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− | |style="background:#ABCDEF;" align="center"|'''Function''' || uptake of oligopeptides
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− | |style="background:#ABCDEF;" align="center"| '''MW, pI''' || 36 kDa, 9.645
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− | |style="background:#ABCDEF;" align="center"| '''Gene length, protein length''' || 987 bp, 329 aa
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− | |style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[appD]]'', ''[[appA]]''
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− | |colspan="2" style="background:#FAF8CC;" align="center"|'''Get the DNA and protein [http://srs.ebi.ac.uk/srsbin/cgi-bin/wgetz?-e+[EMBLCDS:CAB12994]+-newId sequences] <br/> (Barbe ''et al.'', 2009)'''
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− | |colspan="2" | '''Genetic context''' <br/> [[Image:appF_context.gif]]
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− | <div align="right"> <small>This image was kindly provided by [http://genolist.pasteur.fr/SubtiList/ SubtiList]</small></div>
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− | |}
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− | __TOC__
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− | <br/><br/>
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− | =The gene=
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− | === Basic information ===
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− | * '''Locus tag:''' BSU11370
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− | ===Phenotypes of a mutant ===
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− | === Database entries ===
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− | * '''DBTBS entry:''' no entry
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− | * '''SubtiList entry:''' [http://genolist.pasteur.fr/SubtiList/genome.cgi?gene_detail+BG11086]
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− | === Additional information===
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− | =The protein=
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− | === Basic information/ Evolution ===
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− | * '''Catalyzed reaction/ biological activity:'''
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− | * '''Protein family:''' ABC transporter domain (according to Swiss-Prot)
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− | * '''Paralogous protein(s):'''
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− | === Extended information on the protein ===
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− | * '''Kinetic information:'''
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− | * '''Domains:'''
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− | * '''Modification:'''
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− | * '''Cofactor(s):'''
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− | * '''Effectors of protein activity:'''
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− | * '''Interactions:'''
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− | * '''Localization:''' cell membrane (according to Swiss-Prot)
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− | === Database entries ===
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− | * '''Structure:'''
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− | * '''Swiss prot entry:''' [http://www.uniprot.org/uniprot/P42065 P42065]
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− | * '''KEGG entry:''' [http://www.genome.jp/dbget-bin/www_bget?bsu+BSU11370]
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− | * '''E.C. number:'''
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− | === Additional information===
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− | =Expression and regulation=
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− | * '''Operon:''' ''[[appD]]-[[appF]]-[[appA]]-[[appB]]-[[appC]]''
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− | * '''[[Sigma factor]]:'''
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− | * '''Regulation:''' repressed by [[CodY]] [http://www.ncbi.nlm.nih.gov/sites/entrez/12618455 PubMed]
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− | ** repressed during growth in the presence of branched chain amino acids ([[CodY]]) [http://www.ncbi.nlm.nih.gov/sites/entrez/12618455 PubMed]
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− | * '''Regulatory mechanism:''' [[CodY]]: transcription repression [http://www.ncbi.nlm.nih.gov/sites/entrez/12618455 PubMed]
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− | ** [[CodY]]: transcription repression [http://www.ncbi.nlm.nih.gov/sites/entrez/12618455 PubMed]
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− | ** [[CodY]]: transcription repression [http://www.ncbi.nlm.nih.gov/sites/entrez/12618455 PubMed]
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− | * '''Additional information:'''
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− | =Biological materials =
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− | * '''Mutant:'''
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− | * '''Expression vector:'''
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− | * '''lacZ fusion:'''
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− | * '''GFP fusion:'''
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− | * '''two-hybrid system:'''
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− | * '''Antibody:'''
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− | =Labs working on this gene/protein=
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− | =Your additional remarks=
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− | =References=
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− | # Author1, Author2 & Author3 (year) Title ''Journal'' '''volume:''' page-page. [http://www.ncbi.nlm.nih.gov/sites/entrez/PMID PubMed]
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